BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
7/30/2026 7:49:10 AM | Browse: 2 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 119686
Country India
Received
2026-02-03 00:58
Peer-Review Started
2026-02-03 00:58
First Decision by Editorial Office Director
2026-03-04 07:53
Return for Revision
2026-03-04 07:53
Revised
2026-03-09 19:31
Publication Fee Transferred
Second Decision by Editor
2026-04-08 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-08 05:51
Articles in Press
2026-04-08 05:51
Edit the Manuscript by Language Editor
2026-04-14 11:04
Typeset the Manuscript
2026-07-16 09:49
Publish the Manuscript Online
2026-07-30 07:49
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Observational Study
Article Title Anxiety and depression in Rome IV disorders of gut–brain interaction: Prevalence, clinical impact, and temporal association
Manuscript Source Invited Manuscript
All Author List Manjeet Kumar Goyal, Omesh Goyal, Praneet Wander, Jaskirat Kaur, Gargi Prashar, Prerna Goyal and Ajit Sood
ORCID
Author(s) ORCID Number
Manjeet Kumar Goyal http://orcid.org/0000-0002-5511-2099
Omesh Goyal http://orcid.org/0000-0002-6347-0988
Funding Agency and Grant Number
Corresponding Author Omesh Goyal, Department of Gastroenterology, Dayanand Medical College and Hospital, Tagore Nagar, Ludhiana 141001, Punjab, India. goyalomesh@yahoo.co.in
Key Words Anxiety; Depression; Functional bowel disorders; Functional constipation; Functional dyspepsia; Irritable bowel syndrome; Overlap; Quality of life; Rome IV criteria
Core Tip Psychological comorbidities are highly prevalent in disorders of gut-brain interaction (DGBIs), particularly among patients with overlapping syndromes. In this large Rome IV-based cohort, anxiety and depression affected nearly two-thirds and one-third of patients, respectively, with substantially worse quality of life in overlap DGBIs. Notably, gastrointestinal symptoms preceded the onset of anxiety and depression in most cases, supporting a predominant gut-to-brain trajectory. These findings emphasize the need for early identification and proactive management of DGBIs, alongside integrated gut-brain care strategies, to potentially mitigate subsequent psychological morbidity.
Publish Date 2026-07-30 07:49
Citation

Goyal MK, Goyal O, Wander P, Kaur J, Prashar G, Goyal P, Sood A. Anxiety and depression in Rome IV disorders of gut–brain interaction: Prevalence, clinical impact, and temporal association. World J Psychiatry 2026; 16(8): 119686

URL https://www.wjgnet.com/2220-3206/full/v16/i8/119686.htm
DOI https://doi.org/10.5498/wjp.119686
Full Article (PDF) WJP-16-119686-with-cover.pdf
STROBE Statement 119686-STROBE-statement.pdf
Manuscript File 119686_Auto_Edited_004213.docx
Answering Reviewers 119686-answering-reviewers.pdf
Audio Core Tip 119686-audio.mp4
Biostatistics Review Certificate 119686-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 119686-conflict-of-interest-statement.pdf
Copyright License Agreement 119686-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 119686-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 119686-institutional-review-board-statement.pdf
Supplementary Material 119686-supplementary-material.pdf
Peer-review Report 119686-peer-reviews.pdf
Scientific Misconduct Check 119686-scientific-misconduct-check.png
Scientific Editor Work List 119686-scientific-editor-work-list.pdf
CrossCheck Report 119686-crosscheck-report.pdf