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7/9/2026 6:58:22 AM | Browse: 1 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 119692
Country China
Received
2026-02-03 00:26
Peer-Review Started
2026-02-06 09:38
First Decision by Editorial Office Director
2026-03-12 08:16
Return for Revision
2026-03-12 08:16
Revised
2026-03-23 12:23
Publication Fee Transferred
2026-05-19 05:51
Second Decision by Editor
2026-05-18 02:53
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-18 06:44
Articles in Press
2026-05-18 06:44
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-29 14:08
Publish the Manuscript Online
2026-07-09 06:58
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Minireviews
Article Title Diabetic osteoporosis: Focus on ferroptosis as a key player and future prospect in traditional Chinese medicine
Manuscript Source Unsolicited Manuscript
All Author List Xin-Ran Geng and Yang Liu
ORCID
Author(s) ORCID Number
Xin-Ran Geng http://orcid.org/0009-0009-1956-5603
Yang Liu http://orcid.org/0009-0001-6808-3012
Funding Agency and Grant Number
Corresponding Author Yang Liu, Chief Physician, Department of Endocrinology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33 Beiling Street, Huanggu District, Shenyang 110032, Liaoning Province, China. liuyang_linda@163.com
Key Words Diabetic osteoporosis; Ferroptosis; Bone metabolism; Traditional Chinese medicine; Treatment methods
Core Tip Diabetic osteoporosis (DOP) poses high disability and fracture risks, with high-glucose-induced bone cell ferroptosis (driven by iron overload, lipid peroxidation and system Xc⁻/glutathione/glutathione peroxidase 4 imbalance) as its core pathogenesis. Western medicine cannot synergistically improve glucose and bone metabolism and has side effects. This minireview focuses on the high-glucose-bone cell ferroptosis-DOP axis, clarifies ferroptosis mechanisms in key bone cells, and describes how traditional Chinese medicine (TCM) targets ferroptosis via multiple pathways to treat DOP. We bridge TCM theory and the molecular mechanisms of ferroptosis, and discuss TCM-based DOP research directions and clinical translation.
Publish Date 2026-07-09 06:58
Citation

Geng XR, Liu Y. Diabetic osteoporosis: Focus on ferroptosis as a key player and future prospect in traditional Chinese medicine. World J Diabetes 2026; 17(7): 119692

URL https://www.wjgnet.com/1948-9358/full/v17/i7/119692.htm
DOI https://doi.org/10.4239/wjd.119692
Full Article (PDF) WJD-17-119692-with-cover.pdf
Manuscript File 119692_Auto_Edited_084045.docx
Answering Reviewers 119692-answering-reviewers.pdf
Audio Core Tip 119692-audio.mp3
Conflict-of-Interest Disclosure Form 119692-conflict-of-interest-statement.pdf
Copyright License Agreement 119692-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119692-non-native-speakers.pdf
Peer-review Report 119692-peer-reviews.pdf
Scientific Misconduct Check 119692-scientific-misconduct-check.png
Scientific Editor Work List 119692-scientific-editor-work-list.pdf
CrossCheck Report 119692-crosscheck-report.pdf