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Publication Name World Journal of Psychiatry
Manuscript ID 119768
Country China
Received
2026-02-05 01:25
Peer-Review Started
2026-02-05 01:27
First Decision by Editorial Office Director
2026-02-28 06:34
Return for Revision
2026-02-28 06:34
Revised
2026-03-01 12:30
Publication Fee Transferred
Second Decision by Editor
2026-04-02 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-02 05:02
Articles in Press
2026-04-02 05:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-06 03:45
Publish the Manuscript Online
2026-08-24 06:01
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Correspondence
Article Title Letter to the Editor: From discovery to application: Serum 5-hydroxytryptamine for early screening of Parkinson’s complications still faces key challenges
Manuscript Source Unsolicited Manuscript
All Author List Ye-Xiang Chen
ORCID
Author(s) ORCID Number
Ye-Xiang Chen http://orcid.org/0000-0002-1435-4227
Funding Agency and Grant Number
Corresponding Author Ye-Xiang Chen, Academic Fellow, PhD, Postdoctoral Fellow, Department of Pharmacology, College of Medicine, Jiaxing University, No. 899 Guangqiong Road, Jiaxing 314001, Zhejiang Province, China. yexiangchen@zcmu.edu.cn
Key Words Parkinson‘s disease; 5-hydroxytryptamine; Biomarker; Motor dysfunction; Depression
Core Tip Reduced serum 5-hydroxytryptamine levels may indicate an increased risk of both dyskinesia and depression in patients with Parkinson’s disease, suggesting its potential role as a unified screening marker for these complications. However, due to limited validation, as well as the absence of robust longitudinal data and standardized assessment protocols, its clinical applicability remains constrained. Therefore, it should be considered only as an adjunctive biomarker rather than a definitive diagnostic or prognostic indicator at the present stage.
Publish Date 2026-08-24 06:01
Citation

Chen YX. Letter to the Editor: From discovery to application: Serum 5-hydroxytryptamine for early screening of Parkinson’s complications still faces key challenges. World J Psychiatry 2026; 16(9): 119768

URL https://www.wjgnet.com/2220-3206/full/v16/i9/119768.htm
DOI https://doi.org/10.5498/wjp.119768
Full Article (PDF) WJP-16-119768-with-cover.pdf
Manuscript File 119768_Auto_Edited_065725.docx
Answering Reviewers 119768-answering-reviewers.pdf
Audio Core Tip 119768-audio.mp3
Conflict-of-Interest Disclosure Form 119768-conflict-of-interest-statement.pdf
Copyright License Agreement 119768-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119768-non-native-speakers.pdf
Peer-review Report 119768-peer-reviews.pdf
Scientific Misconduct Check 119768-scientific-misconduct-check.png
CrossCheck Report 119768-crosscheck-report.pdf