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Articles Published Processes
10/9/2026 8:15:18 AM | Browse: 1 | Download: 0
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Received |
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2026-02-05 00:45 |
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Peer-Review Started |
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2026-02-05 00:55 |
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First Decision by Editorial Office Director |
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2026-02-12 08:04 |
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Return for Revision |
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2026-02-12 08:04 |
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Revised |
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2026-02-23 17:40 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-03-09 02:57 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-03-09 03:34 |
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Articles in Press |
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2026-03-09 03:34 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-08 06:56 |
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Publish the Manuscript Online |
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2026-10-09 08:15 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Opinion Review |
| Article Title |
Beyond Biomarkers: Prognostic Value of carcinoembryonic antigen and carbohydrate antigen 19-9 in Postoperative Gastric Cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Arunkumar Krishnan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Arunkumar Krishnan, Department of Supportive Oncology, Atrium Health Levine Cancer, Atrium Health Wake Forest Baptist Comprehensive Cancer Center, 1021 Morehead Medical Dr, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com |
| Key Words |
Gastric cancer; Carcinoembryonic antigen; Carbohydrate antigen 19-9; Biomarkers; Recurrence; Chemotherapy toxicity; Statistical methodology; Survival analysis |
| Core Tip |
A recent study by Qi and Wu on CEA and CA19-9 as predictors of gastric cancer recurrence and chemotherapy toxicity is critically evaluated. Although the findings are clinically relevant, several methodological considerations, such as selection bias, temporal ambiguity in biomarker-outcome relationships, insufficient control of confounders, suboptimal survival analysis methods, and limited predictive performance assessment, restrict the clinical generalizability of the findings. There is a need for rigorous multivariable adjustment, proper time-to-event analysis, and validation of clinical utility before these biomarkers can be used to guide individualized postoperative management strategies. |
| Publish Date |
2026-10-09 08:15 |
| Citation |
Krishnan A. Beyond Biomarkers: Prognostic Value of carcinoembryonic antigen and carbohydrate antigen 19-9 in Postoperative Gastric Cancer. World J Gastrointest Oncol 2026; 18(10): 119774
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i10/119774.htm |
| DOI |
https://doi.org/10.4251/wjgo.119774 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
