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5/13/2026 8:18:29 AM | Browse: 6 | Download: 30
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 119843
Country Egypt
Received
2026-02-07 03:07
Peer-Review Started
2026-02-07 03:07
First Decision by Editorial Office Director
2026-02-09 09:28
Return for Revision
2026-02-09 09:28
Revised
2026-02-10 07:26
Publication Fee Transferred
Second Decision by Editor
2026-02-27 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-02-27 07:15
Articles in Press
2026-02-27 07:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-04-24 00:43
Publish the Manuscript Online
2026-05-13 08:18
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pediatrics
Manuscript Type Review
Article Title Pediatric migraine: Neurodevelopmental mechanisms, clinical phenotypes, and modern therapeutics
Manuscript Source Invited Manuscript
All Author List Mohammed Al-Beltagi
ORCID
Author(s) ORCID Number
Mohammed Al-Beltagi http://orcid.org/0000-0002-7761-9536
Funding Agency and Grant Number
Corresponding Author Mohammed Al-Beltagi, Chairman, Consultant, Head, MD, PhD, Professor, Department of Pediatrics, Faculty of Medicine, Tanta University, No. 1 Hassan Radwan Street, Tanta 31511, Algharbia, Egypt. mbelrem@hotmail.com
Key Words Pediatric migraine; Episodic syndromes; Migraine equivalents; Diagnosis; Neuromodulation devices; Calcitonin gene-related peptide monoclonal antibodies; Gepants
Core Tip Pediatric migraine is a common yet underrecognized neurodevelopmental disorder with age-specific clinical phenotypes, mechanisms, and treatment responses. Children are not “small adults”; migraine expression evolves with brain maturation, hormonal changes, and sensory processing, necessitating pediatric-specific diagnostic and therapeutic strategies. Early recognition of migraine equivalents, timely access to acute treatment, and avoidance of medication overuse are essential to prevent chronification. While traditional preventives offer limited efficacy, emerging mechanism-based therapies and neuromodulation devices are reshaping care. A multimodal, individualized approach integrating pharmacologic, behavioral, and educational interventions is critical to improving long-term outcomes.
Publish Date 2026-05-13 08:18
Citation

Al-Beltagi M. Pediatric migraine: Neurodevelopmental mechanisms, clinical phenotypes, and modern therapeutics. World J Clin Pediatr 2026; 15(2): 119843

URL https://www.wjgnet.com/2219-2808/full/v15/i2/119843.htm
DOI https://dx.doi.org/10.5409/wjcp.v15.i2.119843
Full Article (PDF) WJCP-15-119843-with-cover.pdf
Manuscript File 119843_Auto_Edited_070837.docx
Answering Reviewers 119843-answering-reviewers.pdf
Audio Core Tip 119843-audio.mp3
Conflict-of-Interest Disclosure Form 119843-conflict-of-interest-statement.pdf
Copyright License Agreement 119843-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119843-non-native-speakers.pdf
Peer-review Report 119843-peer-reviews.pdf
Scientific Misconduct Check 119843-scientific-misconduct-check.png
Scientific Editor Work List 119843-scientific-editor-work-list.pdf
CrossCheck Report 119843-crosscheck-report.pdf