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5/20/2026 8:53:14 AM | Browse: 2 | Download: 0
Publication Name World Journal of Clinical Oncology
Manuscript ID 119864
Country China
Received
2026-02-09 01:18
Peer-Review Started
2026-02-09 01:21
First Decision by Editorial Office Director
2026-02-12 08:22
Return for Revision
2026-02-12 08:22
Revised
2026-02-17 19:06
Publication Fee Transferred
Second Decision by Editor
2026-03-16 02:39
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-03-16 10:48
Articles in Press
2026-03-16 10:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-03-29 03:40
Publish the Manuscript Online
2026-05-20 08:53
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Integration of pathomics and single-cell omics in pancreatic ductal adenocarcinoma: Applications and clinical translation prospects
Manuscript Source Invited Manuscript
All Author List Xin Yan, Hong-Yu Xu, Jia-Wu Liu, Zhi-Yong Yang and Qian Zhu
ORCID
Author(s) ORCID Number
Hong-Yu Xu http://orcid.org/0009-0001-7758-2040
Qian Zhu http://orcid.org/0000-0002-1203-3278
Funding Agency and Grant Number
Corresponding Author Qian Zhu, PhD, Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, No. 169 East Lake Road, Wuchang District, Wuhan 430071, Hubei Province, China. zhuqian@whu.edu.cn
Key Words Pancreatic ductal adenocarcinoma; Pathomics; Single-cell omics; Artificial intelligence; Multimodal integration
Core Tip This minireview systematically summarizes the progress of single-cell omics and pathomics in pancreatic ductal adenocarcinoma (PDAC) research. Single-cell omics provides deep insights into the cellular heterogeneity, tumor microenvironment, and drug-resistance mechanisms of PDAC. Pathomics employs artificial intelligence to quantitatively analyze histopathological images, enabling automated diagnosis, molecular subtyping, and prognostic evaluation. The integration of these two approaches constructs a multidimensional “morphological-molecular-spatial” perspective, which significantly advances the precision management of PDAC. Future work should focus on standardizing multi-omics techniques, building interpretable models, and promoting clinical translation to address the current therapeutic challenges in PDAC.
Publish Date 2026-05-20 08:53
Citation

Yan X, Xu HY, Liu JW, Yang ZY, Zhu Q. Integration of pathomics and single-cell omics in pancreatic ductal adenocarcinoma: Applications and clinical translation prospects. World J Clin Oncol 2026; 17(5): 119864

URL https://www.wjgnet.com/2218-4333/full/v17/i5/119864.htm
DOI https://dx.doi.org/10.5306/wjco.v17.i5.119864
Full Article (PDF) WJCO-17-119864-with-cover.pdf
Manuscript File 119864_Auto_Edited_075710-YJP.docx
Answering Reviewers 119864-answering-reviewers.pdf
Audio Core Tip 119864-audio.mp3
Conflict-of-Interest Disclosure Form 119864-conflict-of-interest-statement.pdf
Copyright License Agreement 119864-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 119864-non-native-speakers.pdf
Peer-review Report 119864-peer-reviews.pdf
Scientific Misconduct Check 119864-scientific-misconduct-check.png
Scientific Editor Work List 119864-scientific-editor-work-list.pdf
CrossCheck Report 119864-crosscheck-report.pdf