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Articles Published Processes
8/13/2026 7:25:33 AM | Browse: 2 | Download: 0
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Received |
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2026-02-10 00:41 |
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Peer-Review Started |
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2026-02-10 01:08 |
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First Decision by Editorial Office Director |
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2026-02-28 06:58 |
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Return for Revision |
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2026-02-28 06:58 |
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Revised |
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2026-03-04 14:45 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-09 02:32 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-09 08:04 |
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Articles in Press |
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2026-04-09 08:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-06 07:20 |
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Publish the Manuscript Online |
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2026-08-13 07:25 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Case Control Study |
| Article Title |
Potential diagnostic role of urinary exosomal microRNAs in immunoglobulin A nephropathy: A case-control study
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mythri Shankar, Manju Moorthy, Aditya Shetty and Sreedhara C Gurusiddaiah |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Rajiv Gandhi University of Health Sciences |
No. 20MED276 |
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| Corresponding Author |
Mythri Shankar, Associate Professor, Department of Nephrology, Institute of Nephrourology, Victoria Hospital Campus, Bengaluru 560102, Karnataka, India. mythri.nish@gmail.com |
| Key Words |
Immunoglobulin A nephropathy; Urinary exosomal microRNA; Non-invasive biomarker; Indian cohort; Glomerulonephritis; Kidney biopsy |
| Core Tip |
This case-control study evaluates urinary exosomal microRNAs (miRNAs) as noninvasive biomarkers for diagnosing immunoglobulin A nephropathy (IgAN), the most common primary glomerulonephritis. In biopsy-proven IgAN, healthy controls, and diverse glomerular disease controls, a NanoString-based urinary exosomal miRNA panel was profiled, followed by Least Absolute Shrinkage and Selection Operator feature selection, logistic regression, and combinatorial receiver operating characteristic analysis. A focused set of IgAN-associated miRNAs, and a minimal multi-miRNA combination, demonstrated good diagnostic performance to distinguish IgAN from both healthy individuals and other glomerular diseases, suggesting a potential future role for urine exosomal miRNA signatures in reducing reliance on invasive kidney biopsy. |
| Publish Date |
2026-08-13 07:25 |
| Citation |
Shankar M, Moorthy M, Shetty A, Gurusiddaiah SC. Potential diagnostic role of urinary exosomal microRNAs in immunoglobulin A nephropathy: A case-control study. World J Nephrol 2026; 15(3): 119882
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| URL |
https://www.wjgnet.com/2220-6124/full/v15/i3/119882.htm |
| DOI |
https://doi.org/10.5527/wjn.119882 |
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