Publication Name	World Journal of Nephrology
Manuscript ID	11991
Country	Japan

Received	2014-06-18 08:43
Peer-Review Started	2014-06-18 18:07
To Make the First Decision	2014-08-14 15:02
Return for Revision	2014-08-19 13:45
Revised	2015-01-05 00:00
Second Decision	2015-01-28 11:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-02-09 09:27
Articles in Press	2015-02-09 09:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-04-09 17:49
Publish the Manuscript Online	2015-05-08 14:17

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Review
Article Title	Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus
Manuscript Source	Invited Manuscript
All Author List	Junichi Fujii, Toshihiro Kurahashi, Tasuku Konno, Takujiro Homma and Yoshihito Iuchi
Funding Agency and Grant Number	Funding Agency Grant Number Strategic Young Researcher Overseas Visits Program for Accelerating Brain Circulation from the Japan Society for the Promotion of Sciences
Corresponding Author	Junichi Fujii, Professor, Department of Biochemistry and Molecular Biology, Graduate School of Medical Science, Yamagata University, 2-2-2 Iidanishi, Yamagata 990-9585, Japan. jfujii@med.id.yamagata-u.ac.jp
Key Words	Autoimmune hemolytic anemia; Systemic lupus erythematosus; Red blood cells; New Zealand black mouse; NZW mouse
Core Tip	Superoxide dismutase (SOD1) deficient C57BL/6 mice exhibit characteristics similar to autoimmune hemolytic anemia (AIHA) and systemic lupus erythematosus (SLE) at the gerontic stage. An examination of AIHA-prone New Zealand black (NZB) mice indicated that ROS levels in red blood cells are originally high and further elevated during aging. Transgenic overexpression of human SOD1 in erythroid cells effectively suppresses ROS elevation and ameliorates AIHA symptoms in NZB mice. Herein we discuss the association between oxidative stress and SLE pathogenesis based mainly on the genetic and phenotypic characteristics of NZB and NZW mice.
Publish Date	2015-05-08 14:17
Citation	Fujii J, Kurahashi T, Konno T, Homma T, Iuchi Y. Oxidative stress as a potential causal factor for autoimmune hemolytic anemia and systemic lupus erythematosus. World J Nephrol 2015; 4(2): 213-222
URL	http://www.wjgnet.com/2220-6124/full/v4/i2/213.htm
DOI	http://dx.doi.org/10.5527/wjn.v4.i2.213

Full Article (PDF)	WJN-4-213.pdf
Full Article (Word)	WJN-4-213.doc
Manuscript File	11991-Review.doc
Answering Reviewers	11991-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	11991-Conflict-of-interest statement.pdf
Copyright License Agreement	11991-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20140616180855.pdf
Peer-review Report	11991-Peer-review(s).pdf
Scientific Misconduct Check	11991-Scientific misconduct check.pdf
Scientific Editor Work List	11991-Scientific editor work list.pdf