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9/3/2026 2:49:01 AM | Browse: 0 | Download: 0
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Received |
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2026-02-11 01:03 |
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Peer-Review Started |
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2026-02-11 01:04 |
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First Decision by Editorial Office Director |
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2026-02-25 08:30 |
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Return for Revision |
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2026-02-25 08:30 |
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Revised |
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2026-03-11 07:30 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-17 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-17 07:13 |
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Articles in Press |
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2026-06-17 07:13 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-01 05:43 |
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Publish the Manuscript Online |
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2026-09-03 02:49 |
| ISSN |
1949-8454 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Regenerative potential of von Hippel-Lindau tumor suppressor protein
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hiroshi Kanno and Kimihiro Nakahara |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministry of Education, Culture, Sports, Science, and Technology of Japan |
No. 32713 |
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| Corresponding Author |
Hiroshi Kanno, Academic Fellow, MD, PhD, Professor, Department of Neurosurgery, Yokohama City University Graduate School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004, Japan. hiroshikannomd@nifty.com |
| Key Words |
Regeneration; Von Hippel-Lindau; Mesenchymal stem cell; Neuronal disease; Hypoxia-inducible factor |
| Core Tip |
The mechanism of action of von Hippel-Lindau (VHL) involved in neuronal differentiation is mediated through the inhibition of downstream signaling pathways, JAK-STAT, and HIF-VEGF pathways. In addition, because VHL promotes nerve regeneration, it is expected to be applied in neuronal regenerative medicine for traumatic brain injury and stroke. |
| Publish Date |
2026-09-03 02:49 |
| Citation |
Kanno H, Nakahara K. Regenerative potential of von Hippel-Lindau tumor suppressor protein. World J Biol Chem 2026; 17(3): 119936
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| URL |
https://www.wjgnet.com/1949-8454/full/v17/i3/119936.htm |
| DOI |
https://doi.org/10.4331/wjbc.119936 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
