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Articles Published Processes
8/13/2026 7:25:32 AM | Browse: 3 | Download: 0
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Received |
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2026-02-12 03:23 |
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Peer-Review Started |
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2026-02-12 03:24 |
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First Decision by Editorial Office Director |
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2026-03-09 09:07 |
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Return for Revision |
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2026-03-09 09:07 |
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Revised |
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2026-03-20 15:28 |
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Publication Fee Transferred |
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2026-03-23 11:14 |
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Second Decision by Editor |
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2026-04-07 02:40 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-07 06:37 |
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Articles in Press |
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2026-04-07 06:37 |
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Edit the Manuscript by Language Editor |
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2026-04-08 14:21 |
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Typeset the Manuscript |
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2026-08-06 07:20 |
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Publish the Manuscript Online |
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2026-08-13 07:25 |
| ISSN |
2220-6124 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Urology & Nephrology |
| Manuscript Type |
Basic Study |
| Article Title |
Curcumin attenuates high glucose-induced apoptosis in renal tubular epithelial cells by enhancing the Nrf2/heme oxygenase-1 antioxidant pathway
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Li, Lu-Lu Wang, Xiang-Zhi Yu, Sai Xie, Peng-Fei Li, Yang Huang and Pei-Ling Bao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Hubei Province |
NO.2024AFB827 |
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| Corresponding Author |
Pei-Ling Bao, Associate Chief Physician, FACC, Department of Nephrology, Xiaogan Hospital Affiliated to Wuhan University of Science and Technology, No. 6 Square Street, Xiaogan 432000, Hubei Province, China. bpltg2023@126.com |
| Key Words |
Curcumin; Renal tubular epithelial cells; Apoptosis; Nrf2/heme oxygenase-1 signaling pathway; Oxidative stress |
| Core Tip |
Diabetic nephropathy (DN) is the primary cause of end-stage renal disease. Oxidative stress-mediated renal tubular damage plays a significant role in the occurrence and progression of DN. Curcumin, a traditional Chinese medicinal component with antioxidant properties, may have therapeutic effects in the treatment of DN. Through in vivo and in vitro experiments, this study found that curcumin can inhibit renal tubular cell apoptosis in a high-sugar environment by enhancing the Nrf2/heme oxygenase-1 signaling pathway, thereby providing renal protection. |
| Publish Date |
2026-08-13 07:25 |
| Citation |
Li Y, Wang LL, Yu XZ, Xie S, Li PF, Huang Y, Bao PL. Curcumin attenuates high glucose-induced apoptosis in renal tubular epithelial cells by enhancing the Nrf2/heme oxygenase-1 antioxidant pathway. World J Nephrol 2026; 15(3): 119984
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| URL |
https://www.wjgnet.com/2220-6124/full/v15/i3/119984.htm |
| DOI |
https://doi.org/10.5527/wjn.119984 |
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