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Publication Name World Journal of Stem Cells
Manuscript ID 120083
Country Italy
Received
2026-02-14 01:58
Peer-Review Started
2026-02-14 02:01
First Decision by Editorial Office Director
2026-03-26 10:14
Return for Revision
2026-03-26 10:14
Revised
2026-03-30 15:06
Publication Fee Transferred
Second Decision by Editor
2026-04-27 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-07 07:47
Articles in Press
2026-05-07 07:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-05-26 09:33
Publish the Manuscript Online
2026-06-25 08:21
ISSN 1948-0210 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Ophthalmology
Manuscript Type Minireviews
Article Title Stem cells in managing glaucoma
Manuscript Source Invited Manuscript
All Author List Francesco Cappellani, Matteo Capobianco, Federico Visalli, Alessandro Avitabile, Giuseppe Gagliano, Simonetta Gaia Nicolosi, Marieme Khouyyi, Fabiana D’Esposito, Caterina Gagliano and Marco Zeppieri
ORCID
Author(s) ORCID Number
Fabiana D’Esposito http://orcid.org/0000-0002-7938-876X
Caterina Gagliano http://orcid.org/0000-0001-8424-0068
Marco Zeppieri http://orcid.org/0000-0003-0999-5545
Funding Agency and Grant Number
Corresponding Author Marco Zeppieri, Consultant, MD, PhD, Postdoc, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it
Key Words Stem cells; Retinal ganglion cells; Glaucoma; Neuroprotection; Induced pluripotent stem cells; Regenerative medicine; Mesenchymal stem cells
Core Tip Glaucoma is widely acknowledged as a chronic neurodegenerative condition characterized by irreversible loss of retinal ganglion cells, leading to progressive visual deterioration despite good management of intraocular pressure. Stem cell-based approaches present an innovative regenerative framework by delivering neurotrophic support, immunomodulation, and possible cellular replacement. Experimental studies indicate that embryonic, induced pluripotent, and mesenchymal stem cells can extend the survival of retinal ganglion cells and alter the glaucomatous milieu. Despite significant obstacles, stem cell technologies may eventually enhance or transform existing glaucoma treatment protocols.
Publish Date 2026-06-25 08:21
Citation

Cappellani F, Capobianco M, Visalli F, Avitabile A, Gagliano G, Nicolosi SG, Khouyyi M, D’Esposito F, Gagliano C, Zeppieri M. Stem cells in managing glaucoma. World J Stem Cells 2026; 18(6): 120083

URL https://www.wjgnet.com/1948-0210/full/v18/i6/120083.htm
DOI https://doi.org/10.4252/wjsc.120083
Full Article (PDF) WJSC-18-120083-with-cover.pdf
Manuscript File 120083_Auto_Edited_080352.docx
Answering Reviewers 120083-answering-reviewers.pdf
Audio Core Tip 120083-audio.m4a
Conflict-of-Interest Disclosure Form 120083-conflict-of-interest-statement.pdf
Copyright License Agreement 120083-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 120083-non-native-speakers.pdf
Peer-review Report 120083-peer-reviews.pdf
Scientific Misconduct Check 120083-scientific-misconduct-check.png
Scientific Editor Work List 120083-scientific-editor-work-list.pdf
CrossCheck Report 120083-crosscheck-report.pdf