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Articles Published Processes
11/5/2026 2:51:13 AM | Browse: 3 | Download: 1
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Received |
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2026-02-24 08:27 |
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Peer-Review Started |
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2026-02-24 08:28 |
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First Decision by Editorial Office Director |
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2026-03-13 08:08 |
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Return for Revision |
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2026-03-13 08:08 |
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Revised |
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2026-03-27 12:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-17 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-17 05:08 |
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Articles in Press |
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2026-04-17 05:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-10-15 07:30 |
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Publish the Manuscript Online |
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2026-11-05 02:51 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
CD161-lectin-like transcript 1 axis beyond programmed cell death protein 1 in hepatitis B virus-associated hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Hai Nguyen Ngoc Dang, Hau Phuc Tran, Hung Minh Vu, Trung Tran Nguyen, Bich Ngoc Hoang Thi, Thanh Van Ho, Adegbesan Abiodun Christopher, Hung Tran Xuan and Thang Viet Luong |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Thang Viet Luong, Lecturer, MD, Researcher, Menzies Institute for Medical Research, University of Tasmania, Level 1, Medical Science 1/17 Liverpool Street, Hobart 7000, Tasmania, Australia. vietthang.luong@utas.edu.au |
| Key Words |
CD161; Hepatocellular carcinoma; Hepatitis B virus; Immune resistance; T-cell exhaustion; Programmed death-1/programmed death ligand-1 resistance |
| Core Tip |
In hepatitis B virus-associated hepatocellular carcinoma, CD161+CD8+ T cells are enriched in tumor tissue and may persist despite programmed death-1 blockade, suggesting that immune inhibition is not fully explained by the programmed death-1/programmed death ligand-1 axis alone. These observations raise the possibility that the CD161-lectin-like transcript 1 pathway represents a complementary mechanism of adaptive immune resistance. This editorial highlights the importance of protein-level CD161 assessment and discusses the translational relevance of this axis as a potential biomarker and therapeutic target for future investigation. |
| Publish Date |
2026-11-05 02:51 |
| Citation |
Nguyen Ngoc Dang H, Phuc Tran H, Minh Vu H, Tran Nguyen T, Hoang Thi BN, Van Ho T, Abiodun Christopher A, Tran Xuan H, Viet Luong T. CD161-lectin-like transcript 1 axis beyond programmed cell death protein 1 in hepatitis B virus-associated hepatocellular carcinoma. World J Gastrointest Oncol 2026; 18(11): 120101
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| URL |
https://www.wjgnet.com/1948-5204/full/v18/i11/120101.htm |
| DOI |
https://doi.org/10.4251/wjgo.120101 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
