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Articles Published Processes
4/27/2026 8:16:24 AM | Browse: 3 | Download: 15
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Received |
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2026-02-24 06:59 |
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Peer-Review Started |
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2026-02-24 07:01 |
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First Decision by Editorial Office Director |
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2026-03-03 09:23 |
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Return for Revision |
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2026-03-03 09:23 |
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Revised |
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2026-03-10 00:08 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-02 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-02 06:50 |
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Articles in Press |
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2026-04-02 06:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-04-20 01:00 |
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Publish the Manuscript Online |
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2026-04-27 08:16 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Case Report |
| Article Title |
Refractory rosuvastatin-associated necrotizing autoimmune myopathy: A case report and review of literature
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mrudula Thiriveedi, Hersh Patel and Punuru J Reddy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mrudula Thiriveedi, Chief Physician, MD, Department of Internal Medicine, Decatur Morgan Hospital, 1201 7th Street SE, Decatur, AL 35601, United States. drmrudula.giridhar@gmail.com |
| Key Words |
Statin-associated necrotizing autoimmune myopathy; Anti-3-hydroxy-3-methylglutaryl–coenzyme A reductase antibodies; Rosuvastatin; Immune-mediated myopathy; Rhabdomyolysis; Case report |
| Core Tip |
Statin-associated necrotizing autoimmune myopathy (NAM) is a rare immune-mediated myopathy defined by progressive weakness, marked creatine kinase elevation, and persistence of disease activity despite statin withdrawal, most often associated with anti-3-hydroxy-3-methylglutaryl–coenzyme A reductase antibodies. Many patients respond to corticosteroids and intravenous immunoglobulin (IVIG), but refractory disease can occur, particularly when diagnosis is delayed or when severe systemic complications develop. We report an elderly woman receiving long-term rosuvastatin who developed persistent rhabdomyolysis with dialysis-dependent renal failure and died despite high-dose corticosteroids, IVIG, and rituximab. This case underscores the need for early antibody testing and prompt escalation of therapy when statin-associated NAM is suspected, to prevent severe outcomes. |
| Publish Date |
2026-04-27 08:16 |
| Citation |
Thiriveedi M, Patel H, Reddy PJ. Refractory rosuvastatin-associated necrotizing autoimmune myopathy: A case report and review of literature. World J Clin Cases 2026; 14(14): 120126 |
| URL |
https://www.wjgnet.com/2307-8960/full/v14/i14/120126.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v14.i14.120126 |
© 1993-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
