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Articles Published Processes
5/27/2026 3:21:49 AM | Browse: 5 | Download: 13
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Received |
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2026-02-24 07:23 |
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Peer-Review Started |
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2026-02-24 07:25 |
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First Decision by Editorial Office Director |
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2026-02-27 08:57 |
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Return for Revision |
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2026-02-27 08:57 |
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Revised |
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2026-03-05 14:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-01 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-01 04:21 |
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Articles in Press |
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2026-04-01 04:21 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-20 01:24 |
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Publish the Manuscript Online |
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2026-05-27 03:21 |
| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Radiology, Nuclear Medicine & Medical Imaging |
| Manuscript Type |
Minireviews |
| Article Title |
Positron emission tomography tracers in medullary thyroid carcinoma: Current evidence and emerging targets
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fahad W Ahmed and Fauwad Ahmed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Fahad W Ahmed, Consultant, FRCP, PhD, Department of Medical Oncology, King Faisal Specialist Hospital and Research Centre, P.O. Box 3354, Madinah 42522, Saudi Arabia. fahadwali@yahoo.com |
| Key Words |
Medullary thyroid carcinoma; Positron emission tomography; Fluorodihydroxyphenylalanine; Fluorodeoxyglucose; Somatostatin receptor; Calcitonin; Peptide receptor radionuclide therapy; Theranostics |
| Core Tip |
Selecting the right positron emission tomography tracer in medullary thyroid carcinoma depends on tumour biology. This article synthesizes evidence from five databases indicating that fluorodihydroxyphenylalanine remains the most sensitive tracer for recurrent disease, whereas fluorodeoxyglucose better captures aggressive, dedifferentiated tumours. Somatostatin receptor imaging, though less sensitive overall, is indispensable for identifying candidates for peptide receptor radionuclide therapy. We propose an expert-informed, biology-guided algorithm linking biomarker kinetics to tracer choice and highlight cholecystokinin-2 receptor and fibroblast activation protein as promising emerging targets. |
| Publish Date |
2026-05-27 03:21 |
| Citation |
Ahmed FW, Ahmed F. Positron emission tomography tracers in medullary thyroid carcinoma: Current evidence and emerging targets. World J Radiol 2026; 18(5): 120146
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| URL |
https://www.wjgnet.com/1949-8470/full/v18/i5/120146.htm |
| DOI |
https://dx.doi.org/10.4329/wjr.v18.i5.120146 |
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