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7/24/2026 7:03:50 AM | Browse: 1 | Download: 0
Publication Name World Journal of Hepatology
Manuscript ID 120153
Country India
Received
2026-02-24 09:46
Peer-Review Started
2026-02-24 09:47
First Decision by Editorial Office Director
2026-04-08 08:55
Return for Revision
2026-04-09 10:57
Revised
2026-04-23 10:22
Publication Fee Transferred
Second Decision by Editor
2026-06-15 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-15 09:21
Articles in Press
2026-06-15 09:21
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-17 01:09
Publish the Manuscript Online
2026-07-24 07:03
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Saroglitazar ameliorates alcoholic liver disease and is associated with enhanced ethanol metabolism
Manuscript Source Unsolicited Manuscript
All Author List Suresh R Giri, Bibhuti Bhoi, Chitrang Trivedi, Akshyaya Rath, Vighnesh Jadhav, Sandip Palode, Ramchandra Ranvir, Ashvin Patel, Rajesh Sundar, Hiren Patel and Mukul R Jain
ORCID
Author(s) ORCID Number
Suresh R Giri http://orcid.org/0000-0003-0063-5738
Funding Agency and Grant Number
Corresponding Author Suresh R Giri, PhD, Zydus Research Centre, Zydus Lifesciences Limited, Sarkhej-Bavla Highway No. 8A, Moraiya, Ahmedabad 382213, Gujarat, India. sureshgiri@zyduslife.com
Key Words Dual-peroxisome proliferator-activated receptor alpha/gamma agonist; Alcoholic liver disease; Saroglitazar; Alcohol metabolism; National Institute on Alcohol Abuse and Alcoholism mouse model
Core Tip Alcoholic liver disease is one of the major causes of morbidity worldwide and there is an unmet need for a drug to prevent or treat this condition. Saroglitazar, which is approved in India for the treatment of metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, showed beneficial effect like reduction in alanine aminotransferase, aspartate aminotransferase and hepatic triglyceride in animal model of alcoholic liver disease. Saroglitazar effectively altered the alcohol metabolism markers, thus reducing the alcohol-induced liver damage.
Publish Date 2026-07-24 07:03
Citation

Giri SR, Bhoi B, Trivedi C, Rath A, Jadhav V, Palode S, Ranvir R, Patel A, Sundar R, Patel H, Jain MR. Saroglitazar ameliorates alcoholic liver disease and is associated with enhanced ethanol metabolism. World J Hepatol 2026; 18(7): 120153

URL https://www.wjgnet.com/1948-5182/full/v18/i7/120153.htm
DOI https://doi.org/10.4254/wjh.120153
Full Article (PDF) WJH-18-120153-with-cover.pdf
The ARRIVE Guidelines 120153-The-ARRIVE-Guidelines.pdf
Manuscript File 120153_Auto_Edited_020348.docx
Answering Reviewers 120153-answering-reviewers.pdf
Audio Core Tip 120153-audio.aac
Biostatistics Review Certificate 120153-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120153-conflict-of-interest-statement.pdf
Copyright License Agreement 120153-copyright-assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document 120153-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate 120153-non-native-speakers.pdf
Supplementary Material 120153-supplementary-material.pdf
Peer-review Report 120153-peer-reviews.pdf
Scientific Misconduct Check 120153-scientific-misconduct-check.png
Scientific Editor Work List 120153-scientific-editor-work-list.pdf
CrossCheck Report 120153-crosscheck-report.pdf