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6/25/2026 6:40:07 AM | Browse: 1 | Download: 0
Publication Name World Journal of Radiology
Manuscript ID 120177
Country United States
Received
2026-02-24 09:31
Peer-Review Started
2026-02-24 09:31
First Decision by Editorial Office Director
2026-03-12 08:35
Return for Revision
2026-03-12 08:35
Revised
2026-03-17 03:42
Publication Fee Transferred
Second Decision by Editor
2026-05-06 03:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-06 08:01
Articles in Press
2026-05-06 08:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-18 01:46
Publish the Manuscript Online
2026-06-25 06:40
ISSN 1949-8470 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Correspondence
Article Title Letter to the Editor: Hemodynamic role in hepatic encephalopathy pathogenesis following transjugular intrahepatic portosystemic shunt placement
Manuscript Source Unsolicited Manuscript
All Author List John Halphen Jr, Yash S Dayal, Cameron Laurie, Mohadese Ahmadzade, David Wynne and Mohammad Ghasemi-Rad
ORCID
Author(s) ORCID Number
John Halphen Jr http://orcid.org/0009-0000-8524-5530
Mohadese Ahmadzade http://orcid.org/0000-0001-7184-0275
David Wynne http://orcid.org/0000-0001-8881-986X
Mohammad Ghasemi-Rad http://orcid.org/0000-0001-6763-900X
Funding Agency and Grant Number
Corresponding Author Mohammad Ghasemi-Rad, Department of Radiology, Section of Vascular and Interventional Radiology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, United States. mohammad.ghasemirad@bcm.edu
Key Words Arterial spin labeling; Cerebral blood flow; Hemodynamic; Hepatic encephalopathy; Digit symbol substitution test; Resting-state functional magnetic resonance imaging; Transjugular intrahepatic portosystemic shunt
Core Tip The pathogenesis of hepatic encephalopathy (HE) following transjugular intrahepatic portosystemic shunting (TIPS) remains incompletely understood. While hyperammonemia is classically implicated as the driver of HE development, Zhuang et al also suggest that postoperative hemodynamic changes play a key role. Using three-dimensional arterial spin labeling and resting-state functional magnetic resonance imaging, the authors demonstrate brain-region-specific alterations in cerebral blood flow and resting spontaneous brain activity, as measured by amplitude of low-frequency fluctuation, following TIPS placement. Their findings challenge the conventional understanding of post-TIPS placement HE and highlight the diagnostic potential of resting-state functional magnetic resonance imaging for characterizing HE during the early postoperative period.
Publish Date 2026-06-25 06:40
Citation

Halphen Jr J, Dayal YS, Laurie C, Ahmadzade M, Wynne D, Ghasemi-Rad M. Letter to the Editor: Hemodynamic role in hepatic encephalopathy pathogenesis following transjugular intrahepatic portosystemic shunt placement. World J Radiol 2026; 18(6): 120177

URL https://www.wjgnet.com/1949-8470/full/v18/i6/120177.htm
DOI https://doi.org/10.4329/wjr.120177
Full Article (PDF) WJR-18-120177-with-cover.pdf
Manuscript File 120177_Auto_Edited_081312.docx
Answering Reviewers 120177-answering-reviewers.pdf
Audio Core Tip 120177-audio.mp3
Conflict-of-Interest Disclosure Form 120177-conflict-of-interest-statement.pdf
Copyright License Agreement 120177-copyright-assignment.pdf
Peer-review Report 120177-peer-reviews.pdf
Scientific Misconduct Check 120177-scientific-misconduct-check.png
Scientific Editor Work List 120177-scientific-editor-work-list.pdf
CrossCheck Report 120177-crosscheck-report.pdf