Publication Name	World Journal of Gastroenterology
Manuscript ID	12019
Country	South Korea

Received	2014-06-17 20:32
Peer-Review Started	2014-06-17 21:18
First Decision by Editorial Office Director
Return for Revision	2014-07-28 16:19
Revised	2014-08-04 23:31
Publication Fee Transferred
Second Decision by Editor	2014-09-19 09:15
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-09-19 10:01
Articles in Press	2014-09-19 10:31
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-01-15 17:02
Publish the Manuscript Online	2015-01-27 15:33

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Factors associated with significant liver fibrosis assessed using transient elastography in general population
Manuscript Source	Unsolicited Manuscript
All Author List	Seng Chan You, Kwang Joon Kim, Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Won Jae Lee and Kwang-Hyub Han
Funding Agency and Grant Number	Funding Agency Grant Number Liver Cirrhosis Clinical Research Center Korea Healthcare Technology RD Project HI10C2020
Corresponding Author	Seung Up Kim, MD, Department of Internal Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, South Korea. ksukorea@yuhs.ac
Key Words	Carotid artery plaque; Carotid intimal medial th¬ickness; Alanine aminotransferase; Body mass index; Non-alcoholic steatohepatitis; Non-alcoholic fatty liver di¬sease; Liver fibrosis; Fibroscan; Healthy subjects; Transient elastography
Core Tip	This is the first study which investigated the prevalence of significant liver fibrosis assessed using transient elastography and the correlation between comprehensive clinical metabolic parameters (body weight, visceral adiposity, insulin resistance, hepatic steatosis, and atherosclerosis) and the presence of significant liver fibrosis in asymptomatic general subjects. Finally, we found that the prevalence of significant liver fibrosis was fairly high (6.9%) and several factors including higher body mass index, higher alanine aminotransferase, thicker carotid intimal media thickness, and higher numbers of calcified carotid plaques on carotid sonography were significantly correlated to the risk of significant liver fibrosis.
Publish Date	2015-01-27 15:33
Citation	You SC, Kim KJ, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Lee WJ, Han KH. Factors associated with significant liver fibrosis assessed using transient elastography in general population. World J Gastroenterol 2015; 21(4): 1158-1166
URL	http://www.wjgnet.com/1007-9327/full/v21/i4/1158.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i4.1158

Full Article (PDF)	WJG-21-1158.pdf
Full Article (Word)	WJG-21-1158.doc
Manuscript File	12019-Review.docx
Answering Reviewers	12019-Answering reviewers.pdf
Copyright License Agreement	12019-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12019-Language ceftificate.pdf
Peer-review Report	12019-Peer review.pdf
Scientific Misconduct Check	12019-CorssCheck.jpg
Scientific Editor Work List	12019-Scientific editor work list.pdf