| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Recurrence after surgery for hepatocellular carcinoma: “The seed and the soil” - a multicentre retrospective cohort study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Conner Blackmore, Ian Lockart, Geovanny Gandy, Yuen Kang Joseph Yeoh, Ciara Flynn, David S Prince, Gregory Dore, Mark Danta, Jacob George, Maryam Alavi, Yasser Farooque, Behzad Hajarizadeh and Miriam T Levy |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Miriam T Levy, Associate Professor, Department of Gastroenterology, Liverpool Hospital, Corner Elizabeth and Goulburn St, Liverpool 2170, New South Wales, Australia. miriam.levy@health.nsw.gov.au |
| Key Words |
Hepatocellular carcinoma; Prognostic prediction; Surgery; Recurrence; ALBI grade |
| Core Tip |
Recurrence following curative liver resection for hepatocellular carcinoma (HCC) remains a major clinical challenge. In this multicentre retrospective cohort study, cirrhosis, albumin-bilirubin grade ≥ 2, and Barcelona Clinic Liver Cancer stage B/C were independently associated with recurrence. These findings highlight the importance of both tumour burden and underlying liver function when estimating postoperative recurrence risk. Improved preoperative risk stratification may support patient counselling and multidisciplinary decision-making in the management of HCC. |
| Publish Date |
2026-06-26 09:50 |
| Citation |
Blackmore C, Lockart I, Gandy G, Yeoh YKJ, Flynn C, Prince DS, Dore G, Danta M, George J, Alavi M, Farooque Y, Hajarizadeh B, Levy MT. Recurrence after surgery for hepatocellular carcinoma: “The seed and the soil” - a multicentre retrospective cohort study. World J Hepatol 2026; 18(6): 120213
|
| URL |
https://www.wjgnet.com/1948-5182/full/v18/i6/120213.htm |
| DOI |
https://doi.org/10.4254/wjh.120213 |
