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Articles Published Processes
9/10/2026 12:48:59 AM | Browse: 2 | Download: 0
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Received |
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2026-02-24 06:10 |
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Peer-Review Started |
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2026-02-24 06:24 |
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First Decision by Editorial Office Director |
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2026-02-28 09:32 |
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Return for Revision |
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2026-02-28 09:32 |
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Revised |
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2026-03-05 21:21 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-13 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-13 09:11 |
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Articles in Press |
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2026-04-13 09:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-04 02:17 |
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Publish the Manuscript Online |
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2026-09-10 00:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Correspondence |
| Article Title |
Letter to the Editor: Beyond ypN status: Lymph node regression grade refines risk stratification in rectal cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Esther Jimenez Jimenez, Sigfredo E Romero-Zoghbi, Fernando López-Campos and Felipe Couñago |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Felipe Couñago, Department of Radiation Oncology, Genesis Care-San Francisco de Asís University Hospital, Calle de Joaquín Costa, 28, Madrid 28002, Spain. fcounago@gmail.com |
| Key Words |
Lymph node regression; Neoadjuvant chemoradiotherapy; Pathologic nodal status; Rectal cancer; Risk stratification; Total mesorectal excision; Tumor regression grade |
| Core Tip |
Lymph node regression grade offers independent and clinically meaningful prognostic information after neoadjuvant chemoradiotherapy for rectal cancer that is not adequately captured by assessment of primary tumor regression alone. Evaluating nodal treatment response can enhance postoperative risk stratification beyond conventional pathological staging, particularly in patients with residual nodal disease, a subgroup in which therapeutic decision-making remains especially complex. Routine incorporation of lymph node response into standardized pathological reporting may support more precise, individualized adjuvant treatment strategies. However, harmonized histopathological criteria and robust prospective validation are required before widespread clinical implementation. |
| Publish Date |
2026-09-10 00:49 |
| Citation |
Jimenez Jimenez E, Romero-Zoghbi SE, López-Campos F, Couñago F. Letter to the Editor: Beyond ypN status: Lymph node regression grade refines risk stratification in rectal cancer. World J Gastroenterol 2026; 32(39): 120225
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i39/120225.htm |
| DOI |
https://doi.org/10.3748/wjg.v32.i39.120225 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
