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Articles Published Processes
7/20/2026 7:08:31 AM | Browse: 3 | Download: 10
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Received |
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2026-02-24 08:52 |
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Peer-Review Started |
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2026-02-24 08:53 |
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First Decision by Editorial Office Director |
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2026-04-04 02:26 |
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Return for Revision |
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2026-04-04 02:26 |
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Revised |
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2026-05-03 06:02 |
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Publication Fee Transferred |
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2026-05-11 17:44 |
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Second Decision by Editor |
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2026-06-03 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-04 01:08 |
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Articles in Press |
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2026-06-04 01:08 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-15 10:13 |
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Publish the Manuscript Online |
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2026-07-20 07:08 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Circulating microRNAs as biomarkers of cardiovascular disease: A systematic review
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Apurva Popat, Srinivasulu Yerukala Sathipati and Param P Sharma |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Apurva Popat, MD, Department of Cardiology, Marshfield Clinic, 1000 N Oak Ave, Marshfield, WI, 54449, Marshfield, WI 5449, United States. drapurvapopat@gmail.com |
| Key Words |
Cardiovascular disease; MicroRNAs; Biomarkers; Extracellular biomarkers; Precision medicine |
| Core Tip |
This systematic review summarizes current evidence on circulating microRNAs (miRNAs) as diagnostic and prognostic biomarkers across cardiovascular disease, including acute coronary syndromes, coronary artery disease, heart failure, stroke, cardiogenic shock, and hypertension. Several miRNAs showed promising disease-specific signals, including miR-133a, miR-328, miR-423-5p, miR-19a, and miR-21. However, clinical translation remains limited by heterogeneity in sampling methods, assay platforms, normalization strategies, and limited external validation. Standardized multicenter prospective studies are needed before circulating miRNAs can be incorporated into routine cardiovascular risk stratification. |
| Publish Date |
2026-07-20 07:08 |
| Citation |
Popat A, Sathipati SY, Sharma PP. Circulating microRNAs as biomarkers of cardiovascular disease: A systematic review. World J Cardiol 2026; 18(7): 120236
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| URL |
https://www.wjgnet.com/1949-8462/full/v18/i7/120236.htm |
| DOI |
https://doi.org/10.4330/wjc.120236 |
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