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Publication Name World Journal of Gastrointestinal Pharmacology and Therapeutics
Manuscript ID 120256
Country Pakistan
Received
2026-02-24 06:29
Peer-Review Started
2026-02-24 06:32
First Decision by Editorial Office Director
2026-05-18 06:30
Return for Revision
2026-05-18 06:30
Revised
2026-05-31 05:39
Publication Fee Transferred
Second Decision by Editor
2026-06-18 02:31
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-18 06:42
Articles in Press
2026-06-18 06:42
Edit the Manuscript by Language Editor
2026-06-27 23:57
Typeset the Manuscript
2026-08-26 01:12
Publish the Manuscript Online
2026-09-01 04:34
ISSN 2150-5349 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Meta-Analysis
Article Title Hemodynamic safety of remimazolam vs propofol in elderly patients
Manuscript Source Invited Manuscript
All Author List Nawal Tahir, Adil Khan, Sidra Faryal, Muhammad Faizan, Ayesha Irshad, Umer Iqbal, Muaaz Wasay, Syed A Arsal, Aashish kumar, Inibehe I Okon and Shafin Bin Amin
ORCID
Author(s) ORCID Number
Nawal Tahir http://orcid.org/0009-0008-1163-7222
Ayesha Irshad http://orcid.org/0009-0004-5430-2140
Umer Iqbal http://orcid.org/0009-0004-3392-7192
Syed A Arsal http://orcid.org/0000-0002-8665-4288
Aashish kumar http://orcid.org/0000-0003-2277-4050
Funding Agency and Grant Number
Corresponding Author Umer Iqbal, Academic Fellow, Department of Anesthesiology, Pain Management and Surgical Intensive Care, The Indus Hospital, Korangi Campus, Plot C-76, Sector 31/5, Opposite، Crossing, Darussalam Society Sector 39 Korangi, Karachi 75190, Sindh, Pakistan. umer.iqbal@tih.org.pk
Key Words Remimazolam; Propofol; Endoscopy; Colonoscopy; Procedural sedation
Core Tip This meta-analysis of 10 randomized controlled trials involving 1994 elderly patients establishes the superior hemodynamic safety of remimazolam over propofol during gastrointestinal endoscopy. Remimazolam reduced the risk of hypotension by more than half compared to propofol, while significantly lowering incidences of bradycardia, respiratory depression, and injection pain. Crucially, these safety advantages were achieved without compromising recovery times or increasing post-operative nausea. These quantitative findings demonstrate that remimazolam serves as a safer, highly stable sedative alternative for mitigating cardiorespiratory risks in vulnerable older populations.
Publish Date 2026-09-01 04:34
Citation

Tahir N, Khan A, Faryal S, Faizan M, Irshad A, Iqbal U, Wasay M, Arsal SA, kumar A, Okon II, Amin SB. Hemodynamic safety of remimazolam vs propofol in elderly patients. World J Gastrointest Pharmacol Ther 2026; 17(3): 120256

URL https://www.wjgnet.com/2150-5349/full/v17/i3/120256.htm
DOI https://doi.org/10.4292/wjgpt.120256
Full Article (PDF) WJGPT-17-120256-with-cover.pdf
PRISMA 2009 Checklist 120256-PRISMA-2009-Checklist.pdf
Manuscript File 120256_Auto_Edited_013112.docx
Answering Reviewers 120256-answering-reviewers.pdf
Audio Core Tip 120256-audio.m4a
Biostatistics Review Certificate 120256-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120256-conflict-of-interest-statement.pdf
Copyright License Agreement 120256-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 120256-non-native-speakers.pdf
Supplementary Material 120256-supplementary-material.pdf
Peer-review Report 120256-peer-reviews.pdf
Scientific Misconduct Check 120256-scientific-misconduct-check.png
CrossCheck Report 120256-crosscheck-report.pdf