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Publication Name World Journal of Hepatology
Manuscript ID 120258
Country Canada
Received
2026-02-24 09:06
Peer-Review Started
2026-02-24 09:09
First Decision by Editorial Office Director
2026-03-03 09:24
Return for Revision
2026-03-03 09:24
Revised
2026-03-15 19:53
Publication Fee Transferred
Second Decision by Editor
2026-05-29 03:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-29 08:00
Articles in Press
2026-05-29 08:00
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-16 01:03
Publish the Manuscript Online
2026-06-26 09:50
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Machine learning model integrating transient elastography and clinical data for prediction of graft fibrosis after liver transplantation
Manuscript Source Unsolicited Manuscript
All Author List Annabel Koivu, Ghazal Azarfar, Maryam Shojaee, Naomi K T Hlaing, Sameera Rizvi, Divya Sharma, Saba Maleki and Mamatha Bhat
ORCID
Author(s) ORCID Number
Annabel Koivu http://orcid.org/0009-0009-7236-6136
Naomi K T Hlaing http://orcid.org/0000-0002-4237-0603
Mamatha Bhat http://orcid.org/0000-0003-1960-8449
Funding Agency and Grant Number
Corresponding Author Annabel Koivu, MD, Department of Medicine, University Health Network, 500 University Avenue, Suite 602, Toronto ON M5G 1V7, Ontario, Canada. annabel.koivu2@uhn.ca
Key Words Artificial intelligence; Liver transplantation; Graft fibrosis prediction; Transient elastography; Machine learning; Liver stiffness measurements
Core Tip Accurate non-invasive assessment of graft fibrosis after liver-transplantation remains challenging. In this study, we developed an extreme gradient boosting-based machine learning model integrating transient elastography-derived liver stiffness measurements with clinical and laboratory variables to predict clinically significant graft fibrosis. The model demonstrated strong diagnostic performance and highlights the potential of multimodal data integration to improved non-invasive fibrosis assessment in transplant recipients. External validation in multicenter cohorts will be required before clinical implementation.
Publish Date 2026-06-26 09:50
Citation

Koivu A, Azarfar G, Shojaee M, Hlaing NKT, Rizvi S, Sharma D, Maleki S, Bhat M. Machine learning model integrating transient elastography and clinical data for prediction of graft fibrosis after liver transplantation. World J Hepatol 2026; 18(6): 120258

URL https://www.wjgnet.com/1948-5182/full/v18/i6/120258.htm
DOI https://doi.org/10.4254/wjh.120258
Full Article (PDF) WJH-18-120258-with-cover.pdf
STROBE Statement 120258-STROBE-statement.pdf
Manuscript File 120258_Auto_Edited_031639.docx
Answering Reviewers 120258-answering-reviewers.pdf
Audio Core Tip 120258-audio.m4a
Biostatistics Review Certificate 120258-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120258-conflict-of-interest-statement.pdf
Copyright License Agreement 120258-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120258-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120258-institutional-review-board-statement.pdf
Supplementary Material 120258-supplementary-material.pdf
Peer-review Report 120258-peer-reviews.pdf
Scientific Misconduct Check 120258-scientific-misconduct-check.png
Scientific Editor Work List 120258-scientific-editor-work-list.pdf
CrossCheck Report 120258-crosscheck-report.pdf