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7/30/2026 7:49:15 AM | Browse: 1 | Download: 0
Publication Name World Journal of Psychiatry
Manuscript ID 120278
Country China
Received
2026-02-26 02:02
Peer-Review Started
2026-02-26 02:02
First Decision by Editorial Office Director
2026-03-20 10:00
Return for Revision
2026-03-20 10:00
Revised
2026-04-01 17:13
Publication Fee Transferred
2026-06-01 01:23
Second Decision by Editor
2026-05-28 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-28 05:59
Articles in Press
2026-05-28 05:59
Edit the Manuscript by Language Editor
2026-06-08 19:23
Typeset the Manuscript
2026-07-16 09:51
Publish the Manuscript Online
2026-07-30 07:49
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Observational Study
Article Title Assessment of nerve growth factor levels and clinical indicators for outcome prediction in first-episode schizophrenia
Manuscript Source Unsolicited Manuscript
All Author List Wen-Huan Xiao, Mo-Lan Wang, Kuan-Yu Chen, Dou-Dou Yu, Ya-Qin Zhao and Jin-Rong Sun
ORCID
Author(s) ORCID Number
Wen-Huan Xiao http://orcid.org/0009-0008-2931-8684
Mo-Lan Wang http://orcid.org/0009-0002-8905-2327
Kuan-Yu Chen http://orcid.org/0009-0001-4929-8317
Dou-Dou Yu http://orcid.org/0009-0003-9411-6994
Ya-Qin Zhao http://orcid.org/0009-0008-2854-1286
Jin-Rong Sun http://orcid.org/0009-0003-1318-1082
Funding Agency and Grant Number
Funding Agency Grant Number
Yangzhou City Basic Research Program (Joint Special Project) - Health and Wellness Category 2023-2-36, 2023-4-24, 2024-3-31, 2025-2-21
Scientific Research Project of Wutaishan Hospital of Yangzhou, Jiangsu Province WTS2025001, WTS2025003
Corresponding Author Jin-Rong Sun, Department of Psychiatry, Affiliated Wutaishan Hospital of Medical College of Yangzhou University, No. 2 Wutaishan Road, Yangzhou 225003, Jiangsu Province, China. 1723487395@qq.com
Key Words Nerve growth factor; Schizophrenia; First-episode schizophrenia; Treatment outcome; Biomarker
Core Tip This study in first-episode schizophrenia found that baseline serum nerve growth factor (NGF) levels were significantly lower than in healthy controls and increased after 8 weeks of antipsychotic treatment. Baseline NGF, NGF at week 2, early NGF changes, and early psychopathological improvement each independently predicted treatment response. Combining all four indicators yielded superior predictive performance over any single measure, suggesting that dynamic NGF monitoring may assist early clinical decision-making.
Publish Date 2026-07-30 07:49
Citation

Xiao WH, Wang ML, Chen KY, Yu DD, Zhao YQ, Sun JR. Assessment of nerve growth factor levels and clinical indicators for outcome prediction in first-episode schizophrenia. World J Psychiatry 2026; 16(8): 120278

URL https://www.wjgnet.com/2220-3206/full/v16/i8/120278.htm
DOI https://doi.org/10.5498/wjp.120278
Full Article (PDF) WJP-16-120278-with-cover.pdf
STROBE Statement 120278-STROBE-statement.pdf
Manuscript File 120278_Auto_Edited_004321.docx
Answering Reviewers 120278-answering-reviewers.pdf
Audio Core Tip 120278-audio.mp3
Biostatistics Review Certificate 120278-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120278-conflict-of-interest-statement.pdf
Copyright License Agreement 120278-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120278-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120278-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120278-non-native-speakers.pdf
Peer-review Report 120278-peer-reviews.pdf
Scientific Misconduct Check 120278-scientific-misconduct-check.png
Scientific Editor Work List 120278-scientific-editor-work-list.pdf
CrossCheck Report 120278-crosscheck-report.pdf