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8/13/2026 7:25:28 AM | Browse: 2 | Download: 0
Publication Name World Journal of Nephrology
Manuscript ID 120318
Country Egypt
Received
2026-02-24 05:53
Peer-Review Started
2026-02-24 05:54
First Decision by Editorial Office Director
2026-03-06 09:18
Return for Revision
2026-03-06 09:18
Revised
2026-03-17 15:33
Publication Fee Transferred
Second Decision by Editor
2026-05-13 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-13 08:47
Articles in Press
2026-05-13 08:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-04 13:10
Publish the Manuscript Online
2026-08-13 07:25
ISSN 2220-6124 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Observational Study
Article Title Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis
Manuscript Source Invited Manuscript
All Author List Nashwa M Azoz, Ammar A Ammar, Howaida A Nafady, Rabea A Gadelkareem, Essam M Abdel Aziz and Randa A Elzohne
ORCID
Author(s) ORCID Number
Nashwa M Azoz http://orcid.org/0000-0002-8455-1920
Ammar A Ammar http://orcid.org/0009-0002-4706-7125
Howaida A Nafady http://orcid.org/0009-0008-1439-2347
Rabea A Gadelkareem http://orcid.org/0000-0003-4403-2859
Essam M Abdel Aziz http://orcid.org/0009-0008-4149-9991
Randa A Elzohne http://orcid.org/0009-0001-4478-050X
Funding Agency and Grant Number
Corresponding Author Rabea A Gadelkareem, Assistant Professor, Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Elgamaa Street, Assiut 71515, Egypt. rabeagad@aun.edu.eg
Key Words Bone mineral density; Chronic kidney disease; Fibroblast growth factor-23; Lupus nephritis; Renal disease activity; Systemic lupus erythematosus
Core Tip Fibroblast growth factor-23 (FGF-23) regulates mineral metabolism and may reflect both renal activity and skeletal involvement. The present study demonstrated that serum FGF-23 levels were significantly associated with renal disease activity and bone mineral metabolism (BMD) in patients with lupus nephritis. Elevated FGF-23 levels were correlated with impaired renal function and reduced BMD. Therefore, FGF-23 may be a valuable biomarker of renal disease activity and the risk of bone loss. Routine assessment of serum FGF-23 in patients with lupus nephritis may aid in risk stratification and disease monitoring. Additionally, those patients should undergo regular evaluation of BMD and mineral metabolism parameters.
Publish Date 2026-08-13 07:25
Citation

Azoz NM, Ammar AA, Nafady HA, Gadelkareem RA, Abdel Aziz EM, Elzohne RA. Role of fibroblast growth factor-23 in renal disease activity and bone density involvement in patients with lupus nephritis. World J Nephrol 2026; 15(3): 120318

URL https://www.wjgnet.com/2220-6124/full/v15/i3/120318.htm
DOI https://doi.org/10.5527/wjn.v15.i3.120318
Full Article (PDF) WJN-15-120318-with-cover.pdf
STROBE Statement 120318-STROBE-statement.pdf
Manuscript File 120318_Auto_Edited_092121.docx
Answering Reviewers 120318-answering-reviewers.pdf
Audio Core Tip 120318-audio.mp3
Biostatistics Review Certificate 120318-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120318-conflict-of-interest-statement.pdf
Copyright License Agreement 120318-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120318-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120318-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120318-non-native-speakers.pdf
Peer-review Report 120318-peer-reviews.pdf
Scientific Misconduct Check 120318-scientific-misconduct-check.png
Scientific Editor Work List 120318-scientific-editor-work-list.pdf
CrossCheck Report 120318-crosscheck-report.pdf