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Articles Published Processes
9/10/2026 12:48:59 AM | Browse: 2 | Download: 0
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Received |
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2026-02-25 01:37 |
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Peer-Review Started |
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2026-02-25 01:41 |
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First Decision by Editorial Office Director |
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2026-04-08 08:55 |
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Return for Revision |
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2026-04-08 08:55 |
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Revised |
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2026-04-22 08:10 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-12 02:34 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-12 07:44 |
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Articles in Press |
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2026-06-12 07:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-03 01:36 |
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Publish the Manuscript Online |
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2026-09-10 00:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Resolved hepatitis B is associated with higher reactivation risk than chronic infection after chemoembolization for hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dong Yun Kim, Jaehong Jeong, Jung Pyo Hong, Jae Seung Lee, Mi Na Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Do Young Kim and Hye Won Lee |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Faculty Research Grant of Yonsei University College of Medicine |
6-2020-0210 |
| Korea Health Technology R&D Project through the Korea Health Industry Development Institute |
RS-2025-25459146 |
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| Corresponding Author |
Hye Won Lee, Department of Internal Medicine, Yonsei University College of Medicine, 50, Yonsei-ro, Seodaemun-gu, Seoul 03722, South Korea. lorry-lee@yuhs.ac |
| Key Words |
Hepatitis B virus reactivation; Transarterial chemoembolization; Hepatocellular carcinoma; Resolved hepatitis B infection; Anti-hepatitis B core antibody positive |
| Core Tip |
Current international guidelines classify resolved hepatitis B virus (HBV) infection as moderate-risk for reactivation during transarterial chemoembolization, yet our study of 774 patients with confirmed HBV serostatus reveals a 21.3% reactivation rate in hepatitis B surface antigen-negative/anti-hepatitis B core antibody-positive patients, substantially exceeding the moderate-risk threshold. Resolved HBV status was the strongest independent predictor of reactivation (adjusted hazard ratio: 3.98), paradoxically conferring higher risk than chronic infection. These findings challenge existing risk classifications and support prophylactic antiviral therapy rather than monitoring alone for this vulnerable population. |
| Publish Date |
2026-09-10 00:48 |
| Citation |
Kim DY, Jeong J, Hong JP, Lee JS, Kim MN, Kim BK, Kim SU, Park JY, Ahn SH, Kim DY, Lee HW. Resolved hepatitis B is associated with higher reactivation risk than chronic infection after chemoembolization for hepatocellular carcinoma. World J Gastroenterol 2026; 32(39): 120320
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i39/120320.htm |
| DOI |
https://doi.org/10.3748/wjg.120320 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
