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8/25/2026 6:38:35 AM | Browse: 5 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 120350
Country United States
Received
2026-02-24 05:46
Peer-Review Started
2026-02-24 05:48
First Decision by Editorial Office Director
2026-03-27 12:54
Return for Revision
2026-03-27 12:54
Revised
2026-04-04 14:43
Publication Fee Transferred
Second Decision by Editor
2026-05-12 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-12 08:30
Articles in Press
2026-05-12 08:30
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-09 09:40
Publish the Manuscript Online
2026-08-25 06:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Correspondence
Article Title Letter to the Editor: Autoantibody profiling in gastric cancer immunotherapy - dynamic monitoring, toxicity-benefit trade-off, and immune endotypes
Manuscript Source Invited Manuscript
All Author List Wan-Ting Huang, Bin-Bin Zhang and Jia-Nan Zhao
ORCID
Author(s) ORCID Number
Wan-Ting Huang http://orcid.org/0009-0005-5017-8987
Jia-Nan Zhao http://orcid.org/0000-0002-8439-1082
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Funds of China No. 82204827
Corresponding Author Jia-Nan Zhao, Academic Fellow, Department of Cardiovascular Sciences, Temple University, North Carlisle Street, 3440 Carlisle st, Philadelphia, PA 19140, United States. tuv36393@temple.edu
Key Words Gastric cancer; Antinuclear antibody; Extractable nuclear antigen; Immunotherapy; Immune endotype
Core Tip Baseline antinuclear antibody/extractable nuclear antigen status may serve as a potential predictor of immunotherapy outcomes in gastric cancer. However, static indicators fail to capture dynamic autoantibody changes or the underlying differences in immune endotypes. We propose to build a composite host-tumor model that integrates longitudinal antibody profiles, detailed staining patterns, and safety data, and apply calibration curves and decision curve analysis to evaluate its net clinical benefit, thereby promoting the establishment of more refined risk stratification strategies and facilitating the practice of personalized immuno-oncology.
Publish Date 2026-08-25 06:38
Citation

Huang WT, Zhang BB, Zhao JN. Letter to the Editor: Autoantibody profiling in gastric cancer immunotherapy - dynamic monitoring, toxicity-benefit trade-off, and immune endotypes. World J Gastroenterol 2026; 32(36): 120350

URL https://www.wjgnet.com/1007-9327/full/v32/i36/120350.htm
DOI https://doi.org/10.3748/wjg.120350
Full Article (PDF) WJG-32-120350-with-cover.pdf
Manuscript File 120350_Auto_Edited_024611.docx
Answering Reviewers 120350-answering-reviewers.pdf
Audio Core Tip 120350-audio.m4a
Conflict-of-Interest Disclosure Form 120350-conflict-of-interest-statement.pdf
Copyright License Agreement 120350-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 120350-non-native-speakers.pdf
Peer-review Report 120350-peer-reviews.pdf
Scientific Misconduct Check 120350-scientific-misconduct-check.png
CrossCheck Report 120350-crosscheck-report.pdf