| Category |
Transplantation |
| Manuscript Type |
Basic Study |
| Article Title |
Sutureless portal vein reconstruction in porcine orthotopic liver transplantation using a microvascular coupler: A randomized study with artificial intelligence-assisted histopathology
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Jie Li, Jian Yang, Yan Xie, Jia-Ming Shang, Jiang Li, Chi-Yi Chen, Li-Na Liu, Zhong-Ying Zhang, Bing-Hui Pan and Wen-Tao Jiang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Key Project of Scientific Research Plan of Tianjin Municipal Education Commission |
No. 2024ZXZD010 |
| Project of Tianjin Science and Technology Bureau Applied Basic Research |
No. 23JCYBJC01800 |
| Beijing Hepatobiliary Sympathy Foundation Special Fund |
No. iGandan-1082025-RGG009 |
|
| Corresponding Author |
Wen-Tao Jiang, Chief Physician, Dean, Full Professor, Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, No. 2 Baoshan West Road, Xiqing District, Tianjin 300380, China. jiangwentao@nankai.edu.cn |
| Key Words |
Microvascular anastomotic coupler; Sutureless anastomosis; Portal vein reconstruction; Porcine model; Liver transplantation; Artificial intelligence-assisted histopathology |
| Core Tip |
This randomized porcine orthotopic liver transplantation study evaluates a microvascular anastomotic coupler for sutureless portal vein reconstruction. Compared with hand-sewn anastomosis, the coupler shortened anastomosis time by about 12 minutes while maintaining 12-week patency and portal hemodynamics. Quantitative, artificial intelligence-assisted (human-verified) histopathology demonstrated fewer inflammatory cells and smaller necrotic areas around the anastomosis, supporting a favorable local tissue response. These findings indicate that a simple, standardized coupler can reduce warm ischemia and technical variability without sacrificing vascular integrity, offering a practical pathway to streamline portal reconstruction in liver transplantation. |
| Publish Date |
2026-08-17 03:34 |
| Citation |
Li JJ, Yang J, Xie Y, Shang JM, Li J, Chen CY, Liu LN, Zhang ZY, Pan BH, Jiang WT. Sutureless portal vein reconstruction in porcine orthotopic liver transplantation using a microvascular coupler: A randomized study with artificial intelligence-assisted histopathology. World J Gastrointest Surg 2026; 18(8): 120360
|
| URL |
https://www.wjgnet.com/1948-9366/full/v18/i8/120360.htm |
| DOI |
https://doi.org/10.4240/wjgs.120360 |
