6/22/2026 8:40:59 AM | Browse: 1 | Download: 0
| Publication Name | World Journal of Clinical Oncology |
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| Manuscript ID | 120388 |
| Country | Qatar |
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| ISSN | 2218-4333 (online) |
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| Open Access | Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright | ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247 |
| Permissions | For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207 |
| Publisher | Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website | http://www.wjgnet.com |
| Category | Oncology | ||||||||||
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| Manuscript Type | Retrospective Cohort Study | ||||||||||
| Article Title | Evolving patterns of gastrointestinal stromal tumor presentation, management, and outcome over three decades: A middle Eastern Retrospective study | ||||||||||
| Manuscript Source | Unsolicited Manuscript | ||||||||||
| All Author List | Moamena Ahmed El-Matbouly, Hassan Al-Thani, Ayman El-Menyar, Maryam Al-Sulaiti, Mohammad Asim, Mohammad Al Yaseen, Ahmed Suliman, Ahmed Albahrani, Issam Al-Bozom and Abdelhakem Tabeb | ||||||||||
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| Corresponding Author | Ayman El-Menyar, Department of Surgery, Hamad Medical Corporation, Al-Rayyan Street, Doha 3050, Qatar. aymanco65@yahoo.com | ||||||||||
| Key Words | Gastrointestinal stromal tumor; Epidemiology; Minimally Invasive surgical procedures; Imatinib mesylate; Recurrence | ||||||||||
| Core Tip | Gastrointestinal stromal tumors (GIST) represent the most common mesenchymal neoplasms of the gastrointestinal tract, with evolving management driven by advances in molecular profiling, targeted therapy, and minimally invasive surgical techniques. However, longitudinal regional data describing real-world outcomes remain limited. This study aimed to evaluate trends in presentation, surgical management, risk stratification, and outcomes of GIST over three decades in a Middle Eastern country. Gastric primary tumors were the most common GIST. Over three decades, the management of GIST in this regional cohort has evolved toward increased adoption of minimally invasive surgery, molecularly guided therapy, and risk-adapted treatment strategies. High rates of complete resection and favorable disease-free survival highlight the effectiveness of multidisciplinary care. These findings provide region-specific benchmarks to inform clinical practices and future collaborations across multiple centers. | ||||||||||
| Publish Date | 2026-06-22 08:40 | ||||||||||
| Citation |
El-Matbouly MA, Al-Thani H, El-Menyar A, Al-Sulaiti M, Asim M, Al Yaseen M, Suliman A, Albahrani A, Al-Bozom I, Tabeb A. Evolving patterns of gastrointestinal stromal tumor presentation, management, and outcome over three decades: A middle Eastern Retrospective study. World J Clin Oncol 2026; 17(6): 120388 |
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| URL | https://www.wjgnet.com/2218-4333/full/v17/i6/120388.htm | ||||||||||
| DOI | https://doi.org/10.5306/wjco.120388 |
| Full Article (PDF) | WJCO-17-120388-with-cover.pdf |
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| STROBE Statement | 120388-STROBE-statement.pdf |
| Manuscript File | 120388_Auto_Edited_084626.docx |
| Answering Reviewers | 120388-answering-reviewers.pdf |
| Audio Core Tip | 120388-audio.mp3 |
| Biostatistics Review Certificate | 120388-biostatistics-statement.pdf |
| Conflict-of-Interest Disclosure Form | 120388-conflict-of-interest-statement.pdf |
| Copyright License Agreement | 120388-copyright-assignment.pdf |
| Signed Informed Consent Form(s) or Document(s) | 120388-informed-consent-statement.pdf |
| Institutional Review Board Approval Form or Document | 120388-institutional-review-board-statement.pdf |
| Non-Native Speakers of English Editing Certificate | 120388-non-native-speakers.pdf |
| Peer-review Report | 120388-peer-reviews.pdf |
| Scientific Misconduct Check | 120388-scientific-misconduct-check.png |
| Scientific Editor Work List | 120388-scientific-editor-work-list.pdf |
| CrossCheck Report | 120388-crosscheck-report.pdf |