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Articles Published Processes
8/26/2026 5:34:15 AM | Browse: 1 | Download: 0
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Received |
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2026-02-25 02:57 |
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Peer-Review Started |
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2026-02-25 02:58 |
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First Decision by Editorial Office Director |
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2026-03-09 08:54 |
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Return for Revision |
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2026-03-09 08:54 |
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Revised |
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2026-03-22 22:34 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-14 02:36 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-14 07:44 |
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Articles in Press |
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2026-04-14 07:44 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-06 02:48 |
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Publish the Manuscript Online |
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2026-08-26 05:34 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Editorial |
| Article Title |
Landiolol, electrical remodeling, and the emerging biology of ventricular arrhythmia control
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Maryam Salimi, Ramesh Hariharan and Khashayar Hematpour |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Khashayar Hematpour, Department of Advanced Cardiopulmonary Therapies and Transplantations (ACTAT), University of Texas Health Sciences Center, McGovern Medical School, 6400 Fannin St, Houston, TX 77030, United States. khashayar.hematpour@gmail.com |
| Key Words |
Sepsis; Landiolol; Ventricular arrhythmia; Electrical remodeling; Connexin-43; NaV1.5; β1-selective blockade; Conduction heterogeneity |
| Core Tip |
Ventricular arrhythmias in sepsis may not be only a consequence of elevated heart rate, but rather the result of inflammation-driven electrical instability within the myocardium. Experimental data suggest that landiolol may influence this process by affecting key conduction proteins, including connexin-43 and NaV1.5. This perspective shifts the focus from simple rate control toward potential modulation of the arrhythmogenic substrate, highlighting the need for more targeted clinical investigation. |
| Publish Date |
2026-08-26 05:34 |
| Citation |
Salimi M, Hariharan R, Hematpour K. Landiolol, electrical remodeling, and the emerging biology of ventricular arrhythmia control. World J Cardiol 2026; 18(8): 120391
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| URL |
https://www.wjgnet.com/1949-8462/full/v18/i8/120391.htm |
| DOI |
https://doi.org/10.4330/wjc.120391 |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.