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Articles Published Processes
9/15/2026 7:51:40 AM | Browse: 4 | Download: 0
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Received |
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2026-04-08 10:02 |
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Peer-Review Started |
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2026-04-08 10:02 |
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First Decision by Editorial Office Director |
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2026-04-23 03:17 |
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Return for Revision |
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2026-04-23 03:17 |
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Revised |
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2026-05-22 15:25 |
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Publication Fee Transferred |
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2026-05-30 03:35 |
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Second Decision by Editor |
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2026-07-27 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-07-28 13:23 |
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Articles in Press |
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2026-07-28 13:23 |
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Edit the Manuscript by Language Editor |
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2026-08-04 23:56 |
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Typeset the Manuscript |
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2026-09-07 01:26 |
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Publish the Manuscript Online |
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2026-09-15 07:51 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Postoperative circulating tumor DNA detection predicts recurrence and guides adjuvant chemotherapy duration in high-risk stage III colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao-Xi Guo, Jian-Zhong Deng, Long-Qing Cheng, Yi-Ban Lin, Ting Cao, Jie-Lan Feng, Ya-Nan Gao, Xian-Sheng Yang and Shan-Shan Liang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Foshan Self-funded Science and Technology Project |
No. 2220001004876 |
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| Corresponding Author |
Shan-Shan Liang, Department of Gastrointestinal Surgery, The First People’s Hospital of Foshan (Southern University of Science and Technology Affiliated Foshan Hospital), No. 81 Lingnan Avenue, Chancheng District, Foshan 528248, Guangdong Province, China. lsshan5639@163.com |
| Key Words |
Colorectal cancer; Circulating tumor DNA; Recurrence; Adjuvant chemotherapy; Prognosis |
| Core Tip |
Postoperative circulating tumor DNA (ctDNA) provides early risk stratification in high-risk stage III colorectal cancer. In this retrospective cohort of 50 patients with T4 or N2 disease, ctDNA positivity four weeks after surgery was independently associated with poorer recurrence-free survival and earlier recurrence, with an approximately fourfold higher adjusted recurrence risk. Exploratory analyses suggested that ctDNA status may help inform adjuvant capecitabine plus oxaliplatin duration, although no significant within-group difference was observed between 3- and 6-month treatment. These findings support ctDNA as a promising biomarker requiring prospective validation. |
| Publish Date |
2026-09-15 07:51 |
| Citation |
Guo XX, Deng JZ, Cheng LQ, Lin YB, Cao T, Feng JL, Gao YN, Yang XS, Liang SS. Postoperative circulating tumor DNA detection predicts recurrence and guides adjuvant chemotherapy duration in high-risk stage III colorectal cancer. World J Gastrointest Surg 2026; 18(9): 120399
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| URL |
https://www.wjgnet.com/1948-9366/full/v18/i9/120399.htm |
| DOI |
https://doi.org/10.4240/wjgs.120399 |
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