BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
9/22/2026 3:20:34 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 120476
Country Thailand
Received
2026-02-28 01:03
Peer-Review Started
2026-02-28 01:03
First Decision by Editorial Office Director
2026-03-03 09:42
Return for Revision
2026-03-03 09:42
Revised
2026-03-10 07:04
Publication Fee Transferred
2026-03-11 03:28
Second Decision by Editor
2026-04-10 02:46
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-10 07:47
Articles in Press
2026-04-10 07:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-11 02:31
Publish the Manuscript Online
2026-09-22 03:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Tumor protrusion assessment and clinical integration for enhanced mortality risk prediction in spontaneously ruptured hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Wasittee Ajanakitti, Kittipitch Bannangkoon, Teeravut Tubtawee and Natee Ina
ORCID
Author(s) ORCID Number
Kittipitch Bannangkoon http://orcid.org/0000-0003-1926-5239
Teeravut Tubtawee http://orcid.org/0000-0001-7205-7397
Natee Ina http://orcid.org/0000-0002-8565-8973
Funding Agency and Grant Number
Corresponding Author Kittipitch Bannangkoon, Associate Professor, MD, Department of Radiology, Faculty of Medicine, Prince of Songkla University, Kanchanawanit Road, Hat Yai 90110, Songkhla, Thailand. drkittipitch@gmail.com
Key Words Hepatocellular carcinoma; Tumor rupture; Transarterial chemoembolization; Prognosis; Risk score
Core Tip Spontaneously ruptured hepatocellular carcinoma carries a high 30-day mortality risk. Current assessment of tumor protrusion remains largely subjective, and existing prognostic models often lack precision in acute settings. This study identifies “protrusion area” (PA) as a superior predictor of early mortality compared to other metrics. We developed the PA-bilirubin-albumin score, which significantly outperforms conventional scoring systems (area under the receiver operating characteristic curve = 0.813). By stratifying patients into three distinct risk groups, the PA-bilirubin-albumin score provides clinicians with a robust, objective tool for rapid bedside decision-making, helping to identify patients who may benefit more from palliative care than from futile aggressive interventions.
Publish Date 2026-09-22 03:20
Citation

Ajanakitti W, Bannangkoon K, Tubtawee T, Ina N. Tumor protrusion assessment and clinical integration for enhanced mortality risk prediction in spontaneously ruptured hepatocellular carcinoma. World J Gastroenterol 2026; 32(42): 120476

URL https://www.wjgnet.com/1007-9327/full/v32/i42/120476.htm
DOI https://doi.org/10.3748/wjg.120476
Full Article (PDF) WJG-32-120476-with-cover.pdf
STROBE Statement 120476-STROBE-statement.pdf
Manuscript File 120476_Auto_Edited_031531.docx
Answering Reviewers 120476-answering-reviewers.pdf
Audio Core Tip 120476-audio.m4a
Biostatistics Review Certificate 120476-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120476-conflict-of-interest-statement.pdf
Copyright License Agreement 120476-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120476-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120476-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120476-non-native-speakers.pdf
Peer-review Report 120476-peer-reviews.pdf
Scientific Misconduct Check 120476-scientific-misconduct-check.png
CrossCheck Report 120476-crosscheck-report.pdf