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8/17/2026 3:34:37 AM | Browse: 1 | Download: 0
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 120491
Country China
Received
2026-02-27 09:59
Peer-Review Started
2026-02-27 09:59
First Decision by Editorial Office Director
2026-03-12 07:45
Return for Revision
2026-03-12 07:45
Revised
2026-03-31 07:36
Publication Fee Transferred
Second Decision by Editor
2026-07-15 02:53
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-15 06:09
Articles in Press
2026-07-15 06:09
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-05 02:24
Publish the Manuscript Online
2026-08-17 03:34
ISSN 1948-9366 (online)
Open Access Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery
Manuscript Source Unsolicited Manuscript
All Author List Lian-Chao Men, Li-Zeng Wang, Cong-Ying Ma, Ying Zhang and Yu Han
ORCID
Author(s) ORCID Number
Lian-Chao Men http://orcid.org/0009-0003-7630-0923
Yu Han http://orcid.org/0009-0009-6285-4574
Funding Agency and Grant Number
Funding Agency Grant Number
Bethune Public Welfare Foundation - Enze Pain Management Medical Research Project ezmr2024-039
Corresponding Author Yu Han, Department of Critical Care Medicine, Hejian Branch of Cangzhou Central Hospital, No. 32 Jingkai South Street, Cangzhou 062450, Hebei Province, China. hangyudr@163.com
Key Words Oxycodone; Dexmedetomidine; Fentanyl; Sepsis; Gastric perforation; Analgesia; Sedation
Core Tip Sepsis following gastric perforation surgery is associated with high morbidity and prolonged intensive care unit (ICU) stay. Optimizing postoperative analgesia and sedation may influence inflammatory response and organ recovery in these patients. This retrospective cohort study demonstrates that oxycodone combined with dexmedetomidine provides superior analgesia and sedation compared with conventional fentanyl, with improved inflammatory control, enhanced hemodynamic stability, shorter ICU stay, reduced mechanical ventilation duration, and a lower incidence of delirium. These findings support the clinical value of dexmedetomidine-based multimodal analgesia strategies in septic patients after gastric perforation surgery.
Publish Date 2026-08-17 03:34
Citation

Men LC, Wang LZ, Ma CY, Zhang Y, Han Y. Oxycodone-dexmedetomidine vs fentanyl analgesia in septic patients after gastric perforation surgery. World J Gastrointest Surg 2026; 18(8): 120491

URL https://www.wjgnet.com/1948-9366/full/v18/i8/120491.htm
DOI https://doi.org/10.4240/wjgs.120491
Full Article (PDF) WJGS-18-120491-with-cover.pdf
Manuscript File 120491_Auto_Edited_023437.docx
Answering Reviewers 120491-answering-reviewers.pdf
Audio Core Tip 120491-audio.mp3
Biostatistics Review Certificate 120491-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120491-conflict-of-interest-statement.pdf
Copyright License Agreement 120491-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120491-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120491-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120491-non-native-speakers.pdf
Peer-review Report 120491-peer-reviews.pdf
Scientific Misconduct Check 120491-scientific-misconduct-check.png
Scientific Editor Work List 120491-scientific-editor-work-list.pdf
CrossCheck Report 120491-crosscheck-report.pdf