BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
6/22/2026 8:40:59 AM | Browse: 1 | Download: 0
 |
Received |
|
2026-02-28 02:20 |
|
Peer-Review Started |
|
2026-02-28 02:20 |
|
First Decision by Editorial Office Director |
|
2026-04-15 09:09 |
|
Return for Revision |
|
2026-04-15 09:09 |
|
Revised |
|
2026-04-28 15:19 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2026-05-19 02:43 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-05-19 07:37 |
|
Articles in Press |
|
2026-05-19 07:37 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2026-05-28 08:13 |
|
Publish the Manuscript Online |
|
2026-06-22 08:40 |
| ISSN |
2218-4333 (online) |
| Open Access |
Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Enteric neural-tumor interactions in gastrointestinal malignancies and therapeutic implications
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Si-Rui Wang, Ting-Lan Cao, Zeng-Ai Xia and Hui-Zhong Jiang |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Hui-Zhong Jiang, PhD, Professor, Researcher, Department of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, No. 11 North Third Ring Road East, Beijing 100700, China. jianghz93@126.com |
| Key Words |
Enteric nervous system; Gastrointestinal cancer; Tumor microenvironment; Gut-brain axis; Cancer neuroscience |
| Core Tip |
In this review, we propose that the enteric nervous system (ENS) is an active regulator of gastrointestinal malignancies rather than a passive bystander. We summarize how tumors remodel adjacent enteric neuroglial networks and how ENS-derived neurotransmitters and glial signals in turn shape tumor stemness, immune evasion, stromal remodeling, and perineural invasion. We further connect local tumor microenvironment dynamics with systemic brain-gut signaling and highlight druggable neural pathways as potential adjunctive targets for tumor control and symptom management. |
| Publish Date |
2026-06-22 08:40 |
| Citation |
Wang SR, Cao TL, Xia ZA, Jiang HZ. Enteric neural-tumor interactions in gastrointestinal malignancies and therapeutic implications. World J Clin Oncol 2026; 17(6): 120495
|
| URL |
https://www.wjgnet.com/2218-4333/full/v17/i6/120495.htm |
| DOI |
https://doi.org/10.5306/wjco.120495 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
