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7/17/2026 8:23:31 AM | Browse: 1 | Download: 1
Publication Name World Journal of Gastroenterology
Manuscript ID 120498
Country China
Received
2026-02-28 01:48
Peer-Review Started
2026-02-28 01:56
First Decision by Editorial Office Director
2026-04-04 03:06
Return for Revision
2026-04-04 03:06
Revised
2026-04-28 05:18
Publication Fee Transferred
2026-04-30 10:06
Second Decision by Editor
2026-06-08 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-08 07:53
Articles in Press
2026-06-08 07:53
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-13 00:46
Publish the Manuscript Online
2026-07-17 08:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Rapid progression to liver failure following pancreatoduodenectomy in an adolescent: A case report
Manuscript Source Unsolicited Manuscript
All Author List Han Hu, Yu-Juan Liu, Mei-Chuan Li, Yan Li and Shi-De Lin
ORCID
Author(s) ORCID Number
Han Hu http://orcid.org/0000-0001-7604-4008
Shi-De Lin http://orcid.org/0000-0001-8803-4069
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Research Foundation of Zunyi City No. ZSKH-HZ [2023] 222
Guizhou Provincial Science and Technology Program No. QKHJC-ZK [2024] 315
Corresponding Author Shi-De Lin, Chief Physician, MD, Professor, Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, No. 201 Dalian Street, Zunyi 563003, Guizhou Province, China. linshide6@zmu.edu.cn
Key Words Adolescent; Pylorus-preserving pancreatoduodenectomy; Pancreatic exocrine insufficiency; Steatohepatitis; Cirrhosis; Acute-on-chronic liver failure; Case report
Core Tip This report describes a 14-year-old male patient who developed cirrhosis and liver failure after pylorus-preserving pancreatoduodenectomy. Despite pancreatic enzyme replacement therapy, the patient experienced long-term refractory steatorrhea, severe malnutrition, and trace element deficiencies. Malnutrition-associated steatohepatitis and decompensated cirrhosis occurred 4 years postoperatively, followed by progression to liver failure and death from multi-organ dysfunction 2 years later. This case highlights that adolescent patients post-pylorus-preserving pancreatoduodenectomy, due to developmental growth demands, have specific and stringent requirements for pancreatic enzyme replacement and nutritional management. Inadequate management can lead to rapid, fatal progression to cirrhosis and liver failure.
Publish Date 2026-07-17 08:23
Citation

Hu H, Liu YJ, Li MC, Li Y, Lin SD. Rapid progression to liver failure following pancreatoduodenectomy in an adolescent: A case report. World J Gastroenterol 2026; 32(29): 120498

URL https://www.wjgnet.com/1007-9327/full/v32/i29/120498.htm
DOI https://doi.org/10.3748/wjg.120498
Full Article (PDF) WJG-32-120498-with-cover.pdf
CARE Checklist–2016 120498-CARE-Checklist-2016.pdf
Manuscript File 120498_Auto_Edited_021022.docx
Answering Reviewers 120498-answering-reviewers.pdf
Audio Core Tip 120498-audio.mp3
Conflict-of-Interest Disclosure Form 120498-conflict-of-interest-statement.pdf
Copyright License Agreement 120498-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 120498-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 120498-non-native-speakers.pdf
Peer-review Report 120498-peer-reviews.pdf
Scientific Misconduct Check 120498-scientific-misconduct-check.png
Scientific Editor Work List 120498-scientific-editor-work-list.pdf
CrossCheck Report 120498-crosscheck-report.pdf