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Articles Published Processes
7/30/2026 7:49:18 AM | Browse: 1 | Download: 0
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Received |
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2026-02-28 02:17 |
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Peer-Review Started |
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2026-02-28 02:18 |
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First Decision by Editorial Office Director |
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2026-03-17 06:55 |
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Return for Revision |
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2026-03-17 06:55 |
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Revised |
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2026-03-21 11:55 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-06 03:17 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-06 10:18 |
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Articles in Press |
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2026-05-06 10:18 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-17 00:53 |
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Publish the Manuscript Online |
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2026-07-30 07:49 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Nuclear factor-κB as a key inflammatory mediator in psychiatric diseases: A narrative review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fei Fan, Bo Wang, Qiong Wang, Zi-Lin Chen, Wei-Feng Li and Fei Han |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Fundamental Research Funds for the Central Public Welfare Research Institutes |
ZZ17-XRZ-043 |
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| Corresponding Author |
Fei Han, Department of Paediatrics, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Road, Xicheng District, Beijing 100053, China. hf4383@126.com |
| Key Words |
Nuclear factor-κB; Psychiatric diseases; Neuroinflammation; Microglia; Astrocytes; Synaptic plasticity; Immune dysregulation |
| Core Tip |
Nuclear factor-κB (NF-κB) is a central transcription factor linking peripheral immune dysregulation to neuroinflammation in psychiatric disorders. It exerts cell-type-specific effects on microglia, astrocytes, and neurons, interacting with nuclear factor erythroid 2-related factor 2, hypoxia-inducible factor 1-alpha, and NOD-like receptor family pyrin domain containing 3 pathways. Targeting NF-κB and its regulators offers promising therapeutic potential for personalized psychiatry. |
| Publish Date |
2026-07-30 07:49 |
| Citation |
Fan F, Wang B, Wang Q, Chen ZL, Li WF, Han F. Nuclear factor-κB as a key inflammatory mediator in psychiatric diseases: A narrative review. World J Psychiatry 2026; 16(8): 120501
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i8/120501.htm |
| DOI |
https://doi.org/10.5498/wjp.120501 |
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