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7/9/2026 6:58:24 AM | Browse: 1 | Download: 0
Publication Name World Journal of Diabetes
Manuscript ID 120647
Country China
Received
2026-03-05 00:26
Peer-Review Started
2026-03-05 23:55
First Decision by Editorial Office Director
2026-03-27 10:31
Return for Revision
2026-03-27 10:31
Revised
2026-04-09 08:51
Publication Fee Transferred
2026-04-13 02:59
Second Decision by Editor
2026-05-18 02:55
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-09 06:31
Articles in Press
2026-06-09 06:31
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-06-23 09:53
Publish the Manuscript Online
2026-07-09 06:58
ISSN 1948-9358 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Observational Study
Article Title Association between the high-sensitivity C-reactive protein-triglyceride-glucose index and metabolic dysfunction-associated steatotic liver disease across different glycemic states
Manuscript Source Unsolicited Manuscript
All Author List Wen-Hao Zhang, Rong-Dong-Qing Shi, Kui Chen, Xian-Ming Li, Gui-Hua Yu, Xin-Yuan Ye, Qing Xu, Yu Ding and Si-Hui Luo
ORCID
Author(s) ORCID Number
Wen-Hao Zhang http://orcid.org/0009-0008-7007-2444
Rong-Dong-Qing Shi http://orcid.org/0009-0004-5822-2973
Yu Ding http://orcid.org/0000-0003-1617-2125
Si-Hui Luo http://orcid.org/0000-0001-8503-0310
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82300904
National Natural Science Foundation of China 82100857
Corresponding Author Si-Hui Luo, Department of Endocrinology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, 17 Lujiang Road, Hefei 230000, Anhui Province, China. luosihui@ustc.edu.cn
Key Words Metabolic dysfunction-associated steatotic liver disease; High-sensitivity C-reactive protein-triglyceride-glucose index; Glycemic status; Prediabetes; Diabetes; Cross-sectional study
Core Tip This large cross-sectional study (n = 7413) evaluated the high-sensitivity C-reactive protein-triglyceride-glucose index (CTI) as a non-invasive biomarker for metabolic dysfunction-associated steatotic liver disease (MASLD) across glycemic states. The CTI showed robust diagnostic performance (area under the curve: 0.808) with strongest predictive value in normal glucose regulation (adjusted OR = 3.07) and prediabetes (OR = 3.26), but weaker association in diabetes (OR = 1.58). Optimal CTI thresholds increased progressively from normoglycemia to diabetes (8.596, 8.908, 9.456, respectively). These findings suggest CTI is a practical biomarker for early MASLD risk identification, particularly in individuals without overt diabetes.
Publish Date 2026-07-09 06:58
Citation

Zhang WH, Shi RDQ, Chen K, Li XM, Yu GH, Ye XY, Xu Q, Ding Y, Luo SH. Association between the high-sensitivity C-reactive protein-triglyceride-glucose index and metabolic dysfunction-associated steatotic liver disease across different glycemic states. World J Diabetes 2026; 17(7): 120647

URL https://www.wjgnet.com/1948-9358/full/v17/i7/120647.htm
DOI https://doi.org/10.4239/wjd.120647
Full Article (PDF) WJD-17-120647-with-cover.pdf
STROBE Statement 120647-STROBE-statement.pdf
Manuscript File 120647_Auto_Edited_062850.docx
Answering Reviewers 120647-answering-reviewers.pdf
Audio Core Tip 120647-audio.mp3
Biostatistics Review Certificate 120647-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120647-conflict-of-interest-statement.pdf
Copyright License Agreement 120647-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120647-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120647-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120647-non-native-speakers.pdf
Supplementary Material 120647-supplementary-material.pdf
Peer-review Report 120647-peer-reviews.pdf
Journal Editor-in-Chief Review Report 120647-journal-editor-in-chief.pdf
Scientific Misconduct Check 120647-scientific-misconduct-check.png
Scientific Editor Work List 120647-scientific-editor-work-list.pdf
CrossCheck Report 120647-crosscheck-report.pdf