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8/20/2026 6:54:16 AM | Browse: 2 | Download: 13
Publication Name World Journal of Stem Cells
Manuscript ID 120694
Country China
Received
2026-03-27 11:12
Peer-Review Started
2026-03-27 11:12
First Decision by Editorial Office Director
2026-04-15 07:48
Return for Revision
2026-04-15 07:48
Revised
2026-05-01 15:33
Publication Fee Transferred
2026-05-12 09:02
Second Decision by Editor
2026-06-11 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-18 08:16
Articles in Press
2026-06-18 08:16
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-14 01:10
Publish the Manuscript Online
2026-08-20 06:54
ISSN 1948-0210 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Retrospective Study
Article Title Very small embryonic-like stem cells: A predictor synergizing with complement and inflammatory factors for immunoglobulin A nephropathy prognosis
Manuscript Source Unsolicited Manuscript
All Author List Cheng-Li Lou, Ke-Xin Ren, Xiu-Qin Xu, Xiang-Jing Wang, Xiao-Ping Fan, Bo Feng, Ping-Xin Hu and Yi-Jing Zhou
ORCID
Author(s) ORCID Number
Yi-Jing Zhou http://orcid.org/0009-0002-0695-385X
Funding Agency and Grant Number
Funding Agency Grant Number
Zhejiang Provincial Traditional Chinese Medicine Science and Technology Program 2026ZL0854
Corresponding Author Yi-Jing Zhou, Chief Physician, Department of Nephrology, Jiaxing Hospital of Traditional Chinese Medicine, No. 1501 Zhongshan East Road, Jiaxing 314001, Zhejiang Province, China. zyj13967332522@163.com
Key Words Complement alternative pathway; Stem cell indicators; Inflammatory markers; Immunoglobulin A nephropathy; Estimated glomerular filtration rate; End-stage renal disease
Core Tip As a key stem cell indicator, very small embryonic-like stem cells, combined with complement alternative pathway indices and inflammatory biomarker tumor necrosis factor-α, are independent predictors of end-stage renal disease in immunoglobulin A nephropathy patients. Their combined detection yields high predictive accuracy, outperforming single indicators and enabling reliable risk stratification. High very small embryonic-like stem cells correlate with poor renal prognosis, and these serological markers predict outcomes independent of Oxford classification, providing a non-invasive alternative to renal biopsy and enriching individualized intervention biomarkers.
Publish Date 2026-08-20 06:54
Citation

Lou CL, Ren KX, Xu XQ, Wang XJ, Fan XP, Feng B, Hu PX, Zhou YJ. Very small embryonic-like stem cells: A predictor synergizing with complement and inflammatory factors for immunoglobulin A nephropathy prognosis. World J Stem Cells 2026; 18(8): 120694

URL https://www.wjgnet.com/1948-0210/full/v18/i8/120694.htm
DOI https://doi.org/10.4252/wjsc.120694
Full Article (PDF) WJSC-18-120694-with-cover.pdf
Manuscript File 120694_Auto_Edited_020433.docx
Answering Reviewers 120694-answering-reviewers.pdf
Audio Core Tip 120694-audio.mp3
Biostatistics Review Certificate 120694-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120694-conflict-of-interest-statement.pdf
Copyright License Agreement 120694-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 120694-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 120694-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 120694-non-native-speakers.pdf
Peer-review Report 120694-peer-reviews.pdf
Scientific Misconduct Check 120694-scientific-misconduct-check.png
CrossCheck Report 120694-crosscheck-report.pdf