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7/9/2026 6:58:20 AM | Browse: 1 | Download: 0
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Received |
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2026-03-09 01:20 |
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Peer-Review Started |
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2026-03-12 23:47 |
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First Decision by Editorial Office Director |
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2026-03-20 10:11 |
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Return for Revision |
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2026-03-20 10:11 |
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Revised |
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2026-04-02 14:39 |
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Publication Fee Transferred |
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2026-04-07 11:09 |
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Second Decision by Editor |
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2026-05-07 05:50 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-14 09:09 |
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Articles in Press |
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2026-05-14 09:09 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-06-28 03:08 |
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Publish the Manuscript Online |
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2026-07-09 06:58 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Control Study |
| Article Title |
Irisin levels in patients with prediabetes mellitus: A case-control study and meta-analysis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li-Wen Song, Wen-Wen Huang, Li-Na Chang, Xin Wang, Qian-Qian Sun, Xiao-Long Wang and Qing He |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Development Project of the Affiliated Hospital of Weifang Medical University Funds |
2023FYM015 |
| Tianjin Key Medical Discipline (Specialty) Construction Project |
TJYXZDXK-3-002C |
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| Corresponding Author |
Qing He, Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin Medical University General Hospital, 300052, Tianjin, China, Tianjin 300052, China. heqing202301@tmu.edu.cn |
| Key Words |
Irisin; Prediabetes mellitus; Enzyme-linked immunosorbent assay; Methodological variability; Standardization; Case-control study; Meta-analysis |
| Core Tip |
This study suggests that methodological variability between commercial enzyme-linked immunosorbent assay kits may contribute to the conflicting literature on circulating irisin in prediabetes, supported by poor inter assay agreement in this cohort. After rigorously controlling for metabolic confounders, the observed association between prediabetes and irisin disappears, shifting the focus from irisin as a simple biomarker to the critical need for assay standardization and robust study design in future research. |
| Publish Date |
2026-07-09 06:58 |
| Citation |
Song LW, Huang WW, Chang LN, Wang X, Sun QQ, Wang XL, He Q. Irisin levels in patients with prediabetes mellitus: A case-control study and meta-analysis. World J Diabetes 2026; 17(7): 120779
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| URL |
https://www.wjgnet.com/1948-9358/full/v17/i7/120779.htm |
| DOI |
https://doi.org/10.4239/wjd.120779 |
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