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Articles Published Processes
5/29/2026 8:41:34 AM | Browse: 1 | Download: 11
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Received |
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2026-03-10 01:20 |
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Peer-Review Started |
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2026-03-10 01:32 |
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First Decision by Editorial Office Director |
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2026-03-27 10:56 |
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Return for Revision |
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2026-03-27 10:56 |
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Revised |
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2026-03-30 20:45 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-04-09 02:32 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-04-09 09:05 |
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Articles in Press |
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2026-04-09 09:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-05-18 03:59 |
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Publish the Manuscript Online |
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2026-05-29 08:41 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Review |
| Article Title |
Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Christina Mouratidou, Efstathios T Pavlidis, Georgios Katsanos, Athanasios Kofinas, Alexandra G Marneri, Kalliopi E Stavrati, Georgios Tsoulfas and Theodoros E Pavlidis |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Theodoros E Pavlidis, MD, PhD, Professor Emeritus, The Second Department of Propaedeutic Surgery, Hippokration General Hospital, School of Medicine, Aristotle University of Thessaloniki, Konstantinoupoleos 49, Thessaloniki 54642, Greece. pavlidth@auth.gr |
| Key Words |
Hepatic ischemia-reperfusion injury; Liver transplantation; Ferroptosis; Iron metabolism; Lipid peroxidation; Oxidative stress; Hepatocellular injury; Sufentanil |
| Core Tip |
Ferroptosis is critically involved in the pathogenesis of hepatic ischemia-reperfusion injury, primarily through the coordinated disruption of iron homeostasis, lipid peroxidation processes, and antioxidant defense mechanisms. Ferroptosis is characterized by morphological and biochemical features that differentiate it from apoptosis and necrosis; the inhibition of ferroptosis results in the reduction of injury markers, improving liver function in an experimental setting. Beyond its established analgesic properties, sufentanil may confer hepatoprotective effects by modulating pathways associated with ferroptosis. Investigating the interplay between sufentanil and ferroptotic mechanisms could yield valuable therapeutic strategies that enhance clinical outcomes in liver surgery and transplantation. |
| Publish Date |
2026-05-29 08:41 |
| Citation |
Mouratidou C, Pavlidis ET, Katsanos G, Kofinas A, Marneri AG, Stavrati KE, Tsoulfas G, Pavlidis TE. Preconditioning with sufentanil confers protective effects in transplantation by attenuating hepatic ischemia-reperfusion injury. World J Transplant 2026; 16(2): 120865 |
| URL |
https://www.wjgnet.com/2220-3230/full/v16/i2/120865.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v16.i2.120865 |
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