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Articles Published Processes
8/3/2026 1:23:51 AM | Browse: 3 | Download: 0
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Received |
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2026-03-11 03:21 |
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Peer-Review Started |
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2026-03-11 03:22 |
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First Decision by Editorial Office Director |
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2026-03-27 10:26 |
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Return for Revision |
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2026-03-27 10:26 |
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Revised |
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2026-04-17 04:22 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-22 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-22 08:47 |
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Articles in Press |
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2026-06-22 08:47 |
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Edit the Manuscript by Language Editor |
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2026-06-23 14:56 |
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Typeset the Manuscript |
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2026-07-17 00:53 |
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Publish the Manuscript Online |
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2026-08-03 01:23 |
| ISSN |
2219-2808 (online) |
| Open Access |
Open-Access: This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Autologous in vitreo generated plasmin assisted vitrectomy in the pediatric population
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Prema Subramaniam, Ninan Jacob, Veerappan Rathinasabapathy Saravanan, Parag K Shah, Abhishek Das and Narendran Venkatapathy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Parag K Shah, Professor, Department of Pediatric Retina and Ocular Oncology, Postgraduate Institute of Ophthalmology, Aravind Eye Hospital, Avinashi Road, Coimbatore 641014, Tamil Nādu, India. drshahpk2002@yahoo.com |
| Key Words |
Autologous whole blood; Enzymatic vitreolysis; Pediatric vitreo-retinal surgeries; Plasmin; Retinal detachment; Tissue plasminogen activator |
| Core Tip |
Posterior vitreous detachment (PVD) a key to success in all vitreo-retinal surgeries is a crucial and challenging step in pediatric vitreo-retinal surgeries especially syndromic retinal detachments. Surgical success is not fruitful even in experiences hands. Use of enzymatic vitreolysis (with plasmin) is promising in PVD induction, but unfortunately it usage is restricted due to limitation in procuring these less durable enzymes. This method of in vivo plamin generation by injecting readily available agent (autologous whole blood) and tissue plasminogen activator yields plasmin inside the vitreous cavity and help in PVD induction henceforth surgical success. This Retrospective pilot study will be eye opener for practising vitreo-retinal surgeons. |
| Publish Date |
2026-08-03 01:23 |
| Citation |
Subramaniam P, Jacob N, Saravanan VR, Shah PK, Das A, Venkatapathy N. Autologous in vitreo generated plasmin assisted vitrectomy in the pediatric population. World J Clin Pediatr 2026; 15(3): 120868
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| URL |
https://www.wjgnet.com/2219-2808/full/v15/i3/120868.htm |
| DOI |
https://doi.org/10.5409/wjcp.120868 |
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