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Publication Name World Journal of Psychiatry
Manuscript ID 120880
Country China
Received
2026-03-11 03:06
Peer-Review Started
2026-03-11 03:07
First Decision by Editorial Office Director
2026-06-02 08:40
Return for Revision
2026-06-02 08:40
Revised
2026-06-10 15:43
Publication Fee Transferred
2026-06-16 08:39
Second Decision by Editor
2026-07-06 08:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-06 08:47
Articles in Press
2026-07-06 08:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-07-17 00:51
Publish the Manuscript Online
2026-07-30 07:49
ISSN 2220-3206 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Case Report
Article Title Olanzapine-induced restless legs syndrome: Two case reports
Manuscript Source Unsolicited Manuscript
All Author List Hong-Liang Li
ORCID
Author(s) ORCID Number
Hong-Liang Li http://orcid.org/0009-0003-9658-1355
Funding Agency and Grant Number
Corresponding Author Hong-Liang Li, Academic Fellow, Lecturer, Department of Clinic, Jurong Mental Hospital, No. S243 Hongjing Road, Jurong City, Zhenjiang 212400, Jiangsu Province, China. 291413125@qq.com
Key Words Olanzapine; Restless legs syndrome; Schizophrenia; Adverse drug reaction; Case report
Core Tip Olanzapine-induced restless legs syndrome (RLS) is a rare adverse drug reaction with an incidence of only 0.5%-2.3%, easily ignored in psychiatric practice. This article reports two elderly female schizophrenia patients complicated with multiple physical illnesses who developed typical RLS after olanzapine administration. We analyze its possible mechanisms related to dopaminergic dysfunction and abnormal iron metabolism, summarize individualized dose adjustment and antipsychotic switching strategies, and remind clinicians to actively screen RLS symptoms during olanzapine treatment.
Publish Date 2026-07-30 07:49
Citation

Li HL. Olanzapine-induced restless legs syndrome: Two case reports. World J Psychiatry 2026; 16(8): 120880

URL https://www.wjgnet.com/2220-3206/full/v16/i8/120880.htm
DOI https://doi.org/10.5498/wjp.120880
Full Article (PDF) WJP-16-120880-with-cover.pdf
CARE Checklist–2016 120880-CARE-Checklist-2016.pdf
Manuscript File 120880_Auto_Edited_010013.docx
Answering Reviewers 120880-answering-reviewers.pdf
Audio Core Tip 120880-audio.mp3
Conflict-of-Interest Disclosure Form 120880-conflict-of-interest-statement.pdf
Copyright License Agreement 120880-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 120880-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 120880-non-native-speakers.pdf
Peer-review Report 120880-peer-reviews.pdf
Scientific Misconduct Check 120880-scientific-misconduct-check.png
Scientific Editor Work List 120880-scientific-editor-work-list.pdf
CrossCheck Report 120880-crosscheck-report.pdf