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11/3/2026 4:47:29 AM | Browse: 2 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 120932
Country United States
Received
2026-03-12 00:35
Peer-Review Started
2026-03-12 01:55
First Decision by Editorial Office Director
2026-06-09 06:28
Return for Revision
2026-06-09 06:28
Revised
2026-07-26 21:05
Publication Fee Transferred
2026-08-21 17:15
Second Decision by Editor
2026-10-19 06:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-10-20 09:40
Articles in Press
2026-10-20 09:40
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-22 09:22
Publish the Manuscript Online
2026-11-03 04:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Meta-Analysis
Article Title Proton pump inhibitors for gastrointestinal bleeding prevention after percutaneous coronary intervention: Comparing evidence in dual antiplatelet therapy
Manuscript Source Unsolicited Manuscript
All Author List Rohab Sohail, Zaraq Khan, Haider Hussain Shah, Jason Orciuolo, Dwight Fan, Rohan Patel, Ana Estrada Zamudio, Shahryar Chaudhry, Ridda Khattak and Mithil Gowda Suresh
ORCID
Author(s) ORCID Number
Rohab Sohail http://orcid.org/0009-0008-8526-4502
Haider Hussain Shah http://orcid.org/0000-0001-6187-5095
Mithil Gowda Suresh http://orcid.org/0000-0002-1495-5444
Funding Agency and Grant Number
Corresponding Author Rohab Sohail, Department of Internal Medicine, Bayhealth Medical Center, 640 South State Street, Dover, DE 19904, United States. rohabsohail98@gmail.com
Key Words Dual antiplatelet therapy; Percutaneous coronary intervention; Proton pump inhibitors; Gastrointestinal bleeding; All-cause mortality
Core Tip Proton pump inhibitor (PPI) co-therapy remains an effective strategy for preventing upper gastrointestinal (GI) bleeding in patients receiving dual antiplatelet therapy after percutaneous coronary intervention. This systematic review and meta-analysis separately evaluated randomized trials and observational studies, demonstrating consistent protection against upper GI bleeding while highlighting differences in effect estimates across study designs. Observational findings regarding lower GI bleeding, major bleeding, and all-cause mortality should be interpreted cautiously because of lower certainty and potential confounding. These findings support current guideline recommendations for PPI use while emphasizing the need for further high-quality studies to clarify long-term safety and comparative efficacy among individual PPIs.
Publish Date 2026-11-03 04:47
Citation

Sohail R, Khan Z, Hussain Shah H, Orciuolo J, Fan D, Patel R, Estrada Zamudio A, Chaudhry S, Khattak R, Suresh MG. Proton pump inhibitors for gastrointestinal bleeding prevention after percutaneous coronary intervention: Comparing evidence in dual antiplatelet therapy. World J Gastroenterol 2026; 32(48): 120932

URL https://www.wjgnet.com/1007-9327/full/v32/i48/120932.htm
DOI https://doi.org/10.3748/wjg.120932
Full Article (PDF) WJG-32-120932-with-cover.pdf
PRISMA 2009 Checklist 120932-PRISMA-2009-Checklist.pdf
Manuscript File 120932_Auto_Edited_012215.docx
Answering Reviewers 120932-answering-reviewers.pdf
Audio Core Tip 120932-audio.mp3
Biostatistics Review Certificate 120932-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 120932-conflict-of-interest-statement.pdf
Copyright License Agreement 120932-copyright-assignment.pdf
Peer-review Report 120932-peer-reviews.pdf
Scientific Misconduct Check 120932-scientific-misconduct-check.png
CrossCheck Report 120932-crosscheck-report.pdf