Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	12095
Country	Saudi Arabia

Received	2014-06-22 12:51
Peer-Review Started	2014-06-22 22:35
To Make the First Decision	2014-08-14 15:01
Return for Revision	2014-08-19 09:01
Revised	2014-09-02 05:46
Second Decision	2014-10-27 16:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-10-27 17:12
Articles in Press	2014-10-27 17:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-11-04 16:46
Publish the Manuscript Online	2014-11-20 19:04

ISSN	2219-2808 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pediatrics
Manuscript Type	Minireviews
Article Title	Rituximab for troublesome cases of childhood nephrotic syndrome
Manuscript Source	Invited Manuscript
All Author List	Osama Y Safdar, Adila Aboualhameael and Jameela A Kari
Funding Agency and Grant Number
Corresponding Author	Jameela A Kari, FRCP, MD, Department of Pediatrics, King Abdulaziz University, PO Box 80215, Jeddah 21589, Saudi Arabia. jkari@kau.edu.sa
Key Words	Rituximab; Pediatric; Nephrotic syndrome; Efficacy; Safety
Core Tip	Nephrotic syndrome (NS) is the most common pediatric glomerular disease. Although outcomes are favorable, the treatment of complicated nephrotic syndrome can be challenging. Rituximab (RTX) offers a safe and effective alternative to current immunosuppressive therapies for complicated cases of NS. The best outcomes are seen in patients with steroid-dependent NS who have failed to respond to multiple therapies. However, the benefits of RTX therapy are limited in patients with steroid-resistant nephrotic syndrome. Successful RTX therapy induces prolonged remission and enables discontinuation of other medications without increasing the risk of infection and other adverse events.
Publish Date	2014-11-20 19:04
Citation	Safdar OY, Aboualhameael A, Kari JA. Rituximab for troublesome cases of childhood nephrotic syndrome. World J Clin Pediatr 2014; 3(4): 69-75
URL	http://www.wjgnet.com/2219-2808/full/v3/i4/69.htm
DOI	http://dx.doi.org/10.5409/wjcp.v3.i4.69

Full Article (PDF)	WJCP-3-69.pdf
Full Article (Word)	WJCP-3-69.doc
Manuscript File	12095-Review.docx
Answering Reviewers	12095-Answering reviewers.pdf
Copyright License Agreement	12095-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	12095-Language certificate.pdf
Peer-review Report	12095-Peer review(s).pdf
Scientific Misconduct Check	12095-CrossCheck.jpg
Scientific Editor Work List	12095-Scientific editor work list.pdf