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Articles Published Processes
11/20/2014 7:04:00 PM | Browse: 1393 | Download: 2275
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Received |
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2014-06-22 12:51 |
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Peer-Review Started |
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2014-06-22 22:35 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2014-08-19 09:01 |
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Revised |
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2014-09-02 05:46 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2014-10-27 16:54 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2014-10-27 17:12 |
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Articles in Press |
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2014-10-27 17:12 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-11-04 16:46 |
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Publish the Manuscript Online |
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2014-11-20 19:04 |
| Category |
Pediatrics |
| Manuscript Type |
Minireviews |
| Article Title |
Rituximab for troublesome cases of childhood nephrotic syndrome
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Osama Y Safdar, Adila Aboualhameael and Jameela A Kari |
| Funding Agency and Grant Number |
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| Corresponding Author |
Jameela A Kari, FRCP, MD, Department of Pediatrics, King Abdulaziz University, PO Box 80215, Jeddah 21589, Saudi Arabia. jkari@kau.edu.sa |
| Key Words |
Rituximab; Pediatric; Nephrotic syndrome; Efficacy; Safety |
| Core Tip |
Nephrotic syndrome (NS) is the most common pediatric glomerular disease. Although outcomes are favorable, the treatment of complicated nephrotic syndrome can be challenging. Rituximab (RTX) offers a safe and effective alternative to current immunosuppressive therapies for complicated cases of NS. The best outcomes are seen in patients with steroid-dependent NS who have failed to respond to multiple therapies. However, the benefits of RTX therapy are limited in patients with steroid-resistant nephrotic syndrome. Successful RTX therapy induces prolonged remission and enables discontinuation of other medications without increasing the risk of infection and other adverse events. |
| Publish Date |
2014-11-20 19:04 |
| Citation |
Safdar OY, Aboualhameael A, Kari JA. Rituximab for troublesome cases of childhood nephrotic syndrome. World J Clin Pediatr 2014; 3(4): 69-75 |
| URL |
http://www.wjgnet.com/2219-2808/full/v3/i4/69.htm |
| DOI |
http://dx.doi.org/10.5409/wjcp.v3.i4.69 |
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