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Articles Published Processes
8/24/2026 6:01:16 AM | Browse: 0 | Download: 0
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Received |
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2026-03-13 02:10 |
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Peer-Review Started |
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2026-03-13 02:10 |
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First Decision by Editorial Office Director |
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2026-04-10 06:12 |
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Return for Revision |
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2026-04-10 06:12 |
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Revised |
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2026-05-02 12:00 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-26 02:16 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-26 05:34 |
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Articles in Press |
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2026-06-26 05:34 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-07-01 00:40 |
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Publish the Manuscript Online |
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2026-08-24 06:01 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Neural mechanisms and circuit foundations of conscious and unconscious dysfunction in schizophrenia
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Zhao Zhang, Tian-Tian Wang, Jing Zhang, Xin-Yu Wang, Xiao-Hong Liu, Jun Wang and Zhen-He Zhou |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Wuxi Taihu Talent Project |
WXTTP2021 |
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| Corresponding Author |
Zhen-He Zhou, Chief Physician, MD, PhD, Professor, Department of Psychiatry, The Affiliated Mental Health Center of Jiangnan University, No. 156 Qianrong Road, Wuxi 214151, Jiangsu Province, China. zhouzh@jiangnan.edu.cn |
| Key Words |
Schizophrenia; Conscious access; Unconscious processing; Neural mechanisms; Circuit basis |
| Core Tip |
Schizophrenia features a stage-dependent dissociation between conscious and unconscious processing, challenging the simple preserved-implicit vs impaired-explicit dichotomy. While basic subliminal extraction often remains intact, patients exhibit profound deficits in preattentive sensory gating, mismatch negativity, late-stage conscious access, and metacognitive self-evaluation. These abnormalities stem from disrupted large-scale neural synchronization, thalamocortical dysconnectivity, and impaired predictive coding. By mapping these specific circuit-level dysfunctions, this review provides a mechanistic framework linking foundational sensory deficits to clinical psychotic phenomenology, highlighting novel targets for transdiagnostic neuromodulation. |
| Publish Date |
2026-08-24 06:01 |
| Citation |
Zhang JZ, Wang TT, Zhang J, Wang XY, Liu XH, Wang J, Zhou ZH. Neural mechanisms and circuit foundations of conscious and unconscious dysfunction in schizophrenia. World J Psychiatry 2026; 16(9): 120999
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| URL |
https://www.wjgnet.com/2220-3206/full/v16/i9/120999.htm |
| DOI |
https://doi.org/10.5498/wjp.120999 |
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