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Articles Published Processes
9/10/2026 12:49:03 AM | Browse: 2 | Download: 1
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Received |
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2026-03-17 01:30 |
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Peer-Review Started |
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2026-03-17 01:31 |
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First Decision by Editorial Office Director |
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2026-04-29 10:08 |
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Return for Revision |
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2026-04-29 10:08 |
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Revised |
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2026-05-27 12:36 |
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Publication Fee Transferred |
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2026-05-28 13:57 |
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Second Decision by Editor |
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2026-06-15 02:39 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-15 08:04 |
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Articles in Press |
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2026-06-15 08:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-09-03 09:26 |
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Publish the Manuscript Online |
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2026-09-10 00:49 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
Androgen-induced gene 1 correlates with extracellular vesicle-associated cholesterol metabolism and hepatic metastasis of pancreatic cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yun-Zhao Luo, Qing Zhao, Fang-Fei Wang, Jin-Hao Li, Shao-Cheng Lyu, Zhe Liu, Ren Lang and Qiang He |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the Clinical Research Enhancement Program of Beijing Chao-Yang Hospital |
CYTS2025C04 |
| the Research Project of the China Association of Medical Education |
ZJWYH-2023-YIZHI-015 |
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| Corresponding Author |
Qiang He, Chief Physician, PhD, Professor, Division of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongti Nan Lu, Chaoyang District, Beijing 100020, China. heqiang349@163.com |
| Key Words |
Androgen-induced gene 1; Pancreatic ductal adenocarcinoma; Liver metastasis; Small extracellular vesicle; Cholesterol metabolism; Immune remodeling |
| Core Tip |
Active cholesterol metabolism is a hallmark of pancreatic cancer malignancy. Here, we show that tumor-intrinsic androgen-induced gene 1 knockdown disrupts this metabolic program, remodels the hepatic niche away from immunosuppression, and inhibits metastatic growth. Our findings position androgen-induced gene 1 at the intersection of metabolic and immune regulation, warranting further investigation. |
| Publish Date |
2026-09-10 00:49 |
| Citation |
Luo YZ, Zhao Q, Wang FF, Li JH, Lyu SC, Liu Z, Lang R, He Q. Androgen-induced gene 1 correlates with extracellular vesicle-associated cholesterol metabolism and hepatic metastasis of pancreatic cancer. World J Gastroenterol 2026; 32(39): 121007
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| URL |
https://www.wjgnet.com/1007-9327/full/v32/i39/121007.htm |
| DOI |
https://doi.org/10.3748/wjg.121007 |
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