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Articles Published Processes
9/20/2026 4:00:01 AM | Browse: 3 | Download: 6
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Received |
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2026-03-16 03:44 |
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Peer-Review Started |
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2026-03-16 03:45 |
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First Decision by Editorial Office Director |
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2026-04-16 08:17 |
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Return for Revision |
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2026-04-16 08:17 |
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Revised |
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2026-05-18 17:19 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-06-29 02:21 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-06-29 06:53 |
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Articles in Press |
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2026-06-29 06:53 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2026-08-31 09:51 |
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Publish the Manuscript Online |
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2026-09-20 04:00 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Virology |
| Manuscript Type |
Minireviews |
| Article Title |
Junín virus and Argentine haemorrhagic fever: Virology, pathogenesis, diagnosis, and prevention strategies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sita Kumari Karanam, Praveen Kumar Uppala, Naga Vishnu Kandra and Sandhya Edhi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Praveen Kumar Uppala, Department of Pharmacology, Maharajah's College of Pharmacy, Phool Baugh, Vizianagaram 535002, Andhra Pradesh, India. praveen.chintu32@gmail.com |
| Key Words |
Junin virus; Argentine hemorrhagic fever; Arenaviridae; Viral hemorrhagic fever; Rodent reservoirs; Candid 1 vaccine; Viral pathogenesis; Molecular diagnostics |
| Core Tip |
Junin virus is a rodent-borne arenavirus that causes Argentine haemorrhagic fever (AHF), a serious viral disease endemic to agricultural regions of Argentina. The infection spreads mainly through contact with contaminated rodent urine, saliva, or feces, often via inhalation of aerosolized particles. AHF initially presents with fever, fatigue, muscle pain, and headache, but severe cases may progress to bleeding disorders, neurological complications, and cardiovascular instability. The disease pathogenesis involves immune system disruption, vascular injury, and coagulation abnormalities. Diagnosis depends on laboratory methods such as reverse transcription polymerase chain reaction, serological assays, and viral isolation. Early treatment with immune plasma therapy can significantly reduce mortality. Prevention strategies focus on rodent control, safe agricultural practices, public awareness, and vaccination with the Candid #1 vaccine in endemic areas. |
| Publish Date |
2026-09-20 04:00 |
| Citation |
Karanam SK, Uppala PK, Kandra NV, Edhi S. Junín virus and Argentine haemorrhagic fever: Virology, pathogenesis, diagnosis, and prevention strategies. World J Virol 2026; 15(3): 121066
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| URL |
https://www.wjgnet.com/2220-3249/full/v15/i3/121066.htm |
| DOI |
https://doi.org/10.5501/wjv.121066 |
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