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8/20/2026 6:54:16 AM | Browse: 2 | Download: 13
Publication Name World Journal of Stem Cells
Manuscript ID 121124
Country China
Received
2026-04-10 09:57
Peer-Review Started
2026-04-10 09:57
First Decision by Editorial Office Director
2026-04-27 09:24
Return for Revision
2026-04-27 09:24
Revised
2026-05-12 04:44
Publication Fee Transferred
2026-05-15 07:20
Second Decision by Editor
2026-06-12 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-22 09:13
Articles in Press
2026-06-22 09:13
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-14 01:09
Publish the Manuscript Online
2026-08-20 06:54
ISSN 1948-0210 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Retrospective Study
Article Title Stem/progenitor cell-driven immune microenvironment remodeling in sepsis-associated acute respiratory distress syndrome
Manuscript Source Unsolicited Manuscript
All Author List Wen-Xing Li, Si-Cong Jiang, Sheng-Li Fan, Yu-Xuan Xing and Lei Gong
ORCID
Author(s) ORCID Number
Wen-Xing Li http://orcid.org/0009-0004-9376-2457
Lei Gong http://orcid.org/0000-0001-7405-1386
Funding Agency and Grant Number
Corresponding Author Lei Gong, PhD, Department of Esophageal Cancer, Tianjin Medical University Cancer Institute and Hospital, Huanhu West Road, Hexi District, Tianjin 300060, China. pear0721@163.com
Key Words Sepsis; Acute respiratory distress syndrome; Alveolar epithelial type II cells; Progenitor cells; Inflammatory factors; Lactic acid; Prognosis
Core Tip In sepsis-acute respiratory distress syndrome, the downregulation of alveolar epithelial type II cells progenitor markers (surfactant protein C, epithelial cell adhesion molecule) is accompanied by T-cell subset imbalance and elevated proinflammatory cytokines, which are closely associated with disease severity, oxygenation impairment and increased lactate; surfactant protein C and sequential organ failure assessment score are independent predictors of 28-day mortality, suggesting that stem/progenitor cell-mediated immune microenvironment remodeling may serve as a promising prognostic indicator and therapeutic target for sepsis-acute respiratory distress syndrome.
Publish Date 2026-08-20 06:54
Citation

Li WX, Jiang SC, Fan SL, Xing YX, Gong L. Stem/progenitor cell-driven immune microenvironment remodeling in sepsis-associated acute respiratory distress syndrome. World J Stem Cells 2026; 18(8): 121124

URL https://www.wjgnet.com/1948-0210/full/v18/i8/121124.htm
DOI https://doi.org/10.4252/wjsc.121124
Full Article (PDF) WJSC-18-121124-with-cover.pdf
Manuscript File 121124_Auto_Edited_020432.docx
Answering Reviewers 121124-answering-reviewers.pdf
Audio Core Tip 121124-audio.mp3
Biostatistics Review Certificate 121124-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121124-conflict-of-interest-statement.pdf
Copyright License Agreement 121124-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121124-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121124-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121124-non-native-speakers.pdf
Peer-review Report 121124-peer-reviews.pdf
Scientific Misconduct Check 121124-scientific-misconduct-check.png
CrossCheck Report 121124-crosscheck-report.pdf