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10/15/2026 5:45:56 AM | Browse: 1 | Download: 2
Publication Name World Journal of Gastroenterology
Manuscript ID 121126
Country China
Received
2026-03-17 02:30
Peer-Review Started
2026-03-17 02:30
First Decision by Editorial Office Director
2026-04-04 03:32
Return for Revision
2026-04-04 03:32
Revised
2026-04-15 03:21
Publication Fee Transferred
2026-04-16 06:50
Second Decision by Editor
2026-04-24 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-24 10:48
Articles in Press
2026-04-24 10:48
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-10-08 00:16
Publish the Manuscript Online
2026-10-15 05:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Peptide receptor radionuclide therapy for recurrent neuroendocrine tumors after liver transplantation
Manuscript Source Unsolicited Manuscript
All Author List Qi-Ming Zheng, Chi-Yi Chen, Li Zhang, Ji-San Sun, Hong-Hai Wang, Yan Xie, Qing-Jun Guo and Wen-Tao Jiang
ORCID
Author(s) ORCID Number
Qi-Ming Zheng http://orcid.org/0000-0003-4967-2054
Wen-Tao Jiang http://orcid.org/0000-0002-2064-6760
Funding Agency and Grant Number
Funding Agency Grant Number
Key Project of Tianjin Science and Technology Bureau Applied Basic Research No. 23JCZDJC01200
Independent Research Fund of the Institute of Transplant Medicine at Nankai University No. NKTM2023004
Tianjin Key Medical Discipline Construction Project No. TJYXZDXK-3-006A-1
Corresponding Author Wen-Tao Jiang, MD, PhD, Principal Investigator, Department of Liver Transplantation, First Central Hospital of Tianjin Medical University, No. 2 Baoshan West Road, Xiqing District, Tianjin 300192, China. jiangwentao@nankai.edu.cn
Key Words Liver transplantation; Neuroendocrine tumors; Liver metastasis; Peptide receptor radionuclide therapy; Recurrence; Progression-free survival
Core Tip This retrospective comparative cohort study evaluates lutetium Lu 177 dotatate (177Lu-DOTATATE) peptide receptor radionuclide therapy (PRRT) combined with everolimus in somatostatin receptor-positive G2 neuroendocrine tumor liver metastases after liver transplantation. In 7 PRRT-treated patients vs 8 controls, PRRT achieved a disease control rate of 85.7% and significantly improved progression-free survival (log-rank P = 0.028), with manageable hematologic toxicity (grade III in 28.6%) and no graft rejection. These hypothesis-generating findings suggest PRRT as a promising option for this rare cohort.
Publish Date 2026-10-15 05:45
Citation

Zheng QM, Chen CY, Zhang L, Sun JS, Wang HH, Xie Y, Guo QJ, Jiang WT. Peptide receptor radionuclide therapy for recurrent neuroendocrine tumors after liver transplantation. World J Gastroenterol 2026; 32(45): 121126

URL https://www.wjgnet.com/1007-9327/full/v32/i45/121126.htm
DOI https://doi.org/10.3748/wjg.121126
Full Article (PDF) WJG-32-121126-with-cover.pdf
Manuscript File 121126_Auto_Edited_010350.docx
Answering Reviewers 121126-answering-reviewers.pdf
Audio Core Tip 121126-audio.mp3
Biostatistics Review Certificate 121126-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 121126-conflict-of-interest-statement.pdf
Copyright License Agreement 121126-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 121126-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 121126-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 121126-non-native-speakers.pdf
Supplementary Material 121126-supplementary-material.pdf
Peer-review Report 121126-peer-reviews.pdf
Scientific Misconduct Check 121126-scientific-misconduct-check.png
CrossCheck Report 121126-crosscheck-report.pdf