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8/21/2026 3:32:19 AM | Browse: 4 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 121133
Country China
Received
2026-03-26 01:37
Peer-Review Started
2026-03-26 01:37
First Decision by Editorial Office Director
2026-04-10 10:24
Return for Revision
2026-04-10 10:24
Revised
2026-05-03 16:53
Publication Fee Transferred
2026-05-18 13:07
Second Decision by Editor
2026-07-06 08:06
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-07-06 09:42
Articles in Press
2026-07-06 09:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-08-03 07:36
Publish the Manuscript Online
2026-08-21 03:32
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Nanotechnology for drug delivery systems in colorectal cancer: Recent developments and future prospects
Manuscript Source Unsolicited Manuscript
All Author List Zhen-Huan Yang, Quan-Li Huang, Lei Luo, Xing-Xing Wu, Shan-Wen Nie and Man-Man Xu
ORCID
Author(s) ORCID Number
Zhen-Huan Yang http://orcid.org/0000-0002-0919-6180
Man-Man Xu http://orcid.org/0000-0003-4222-9850
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82305074
Doctoral Research Fund of Henan Provincial Hospital of Traditional Chinese Medicine 2022BJSS02
Special Project on Traditional Chinese Medicine Scientific Research of Health Commission of Henan Province 2022ZY1077
Corresponding Author Man-Man Xu, MD, Department of Oncology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China. manmanxu123@126.com
Key Words Nanotechnology; Colorectal cancer; Drug delivery; Tumor microenvironment; Immune
Core Tip This review systematically summarizes recent studies on diverse nano-biomaterials, which are designed for targeted and controlled drug delivery in colorectal cancer. We specifically highlight current advances in nanomedicine-based immunotherapy, focusing on targeting of immunosenescence to reprogram immunosuppression in the tumor microenvironment and improve immune checkpoint inhibitor effects. We further discuss the problems and potential of translating such nanoplatforms into clinical practice. In summary, the present work sheds new lights on those strategies for treating colorectal cancer using nanodrug delivery technology.
Publish Date 2026-08-21 03:32
Citation

Yang ZH, Huang QL, Luo L, Wu XX, Nie SW, Xu MM. Nanotechnology for drug delivery systems in colorectal cancer: Recent developments and future prospects. World J Gastroenterol 2026; 32(35): 121133

URL https://www.wjgnet.com/1007-9327/full/v32/i35/121133.htm
DOI https://doi.org/10.3748/wjg.121133
Full Article (PDF) WJG-32-121133-with-cover.pdf
Manuscript File 121133_Auto_Edited_020000.docx
Answering Reviewers 121133-answering-reviewers.pdf
Audio Core Tip 121133-audio.m4a
Conflict-of-Interest Disclosure Form 121133-conflict-of-interest-statement.pdf
Copyright License Agreement 121133-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121133-non-native-speakers.pdf
Peer-review Report 121133-peer-reviews.pdf
Scientific Misconduct Check 121133-scientific-misconduct-check.png
CrossCheck Report 121133-crosscheck-report.pdf