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10/9/2026 4:02:29 AM | Browse: 1 | Download: 1
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 121145
Country India
Received
2026-03-17 02:59
Peer-Review Started
2026-03-17 02:59
First Decision by Editorial Office Director
2026-04-15 09:05
Return for Revision
2026-04-15 09:05
Revised
2026-04-23 07:33
Publication Fee Transferred
Second Decision by Editor
2026-05-27 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-27 06:35
Articles in Press
2026-05-27 06:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-09-14 08:26
Publish the Manuscript Online
2026-10-09 04:02
ISSN 2219-2808 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Editorial
Article Title Intravenous immunoglobulin in pediatric critical care: Bridging evidence gaps and guiding rational use
Manuscript Source Invited Manuscript
All Author List Amit Agrawal
ORCID
Author(s) ORCID Number
Amit Agrawal http://orcid.org/0000-0001-6316-6700
Funding Agency and Grant Number
Corresponding Author Amit Agrawal, Associate Professor, Department of Pediatrics, Gandhi Medical College, Hamidia Hospital Campus, 49-B Indrapuri, B-Sector, Bhopal 462001, Madhya Pradesh, India. agrawaldramit@yahoo.co.in
Key Words Children; Intravenous immunoglobulin; Immunomodulation; Mortality; Off-label use; Pediatric intensive care; Side effects
Core Tip Intravenous immunoglobulin is increasingly being utilized in pediatric intensive care units for its diverse immunomodulatory effects, even beyond established indications. The study by Varadarajan et al highlights substantial off-label use with only a few adverse effects. This editorial provides a practical, evidence-based framework for the use of intravenous immunoglobulin in critically ill children, including indications, strength of evidence, and stewardship principles to guide its rational use.
Publish Date 2026-10-09 04:02
Citation

Agrawal A. Intravenous immunoglobulin in pediatric critical care: Bridging evidence gaps and guiding rational use. World J Clin Pediatr 2026; 15(4): 121145

URL https://www.wjgnet.com/2219-2808/full/v15/i4/121145.htm
DOI https://doi.org/10.5409/wjcp.121145
Full Article (PDF) WJCP-15-121145-with-cover.pdf
Manuscript File 121145_Auto_Edited_014931.docx
Answering Reviewers 121145-answering-reviewers.pdf
Audio Core Tip 121145-audio.mp4
Conflict-of-Interest Disclosure Form 121145-conflict-of-interest-statement.pdf
Copyright License Agreement 121145-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 121145-non-native-speakers.pdf
Peer-review Report 121145-peer-reviews.pdf
Scientific Misconduct Check 121145-scientific-misconduct-check.png
CrossCheck Report 121145-crosscheck-report.pdf